Wolff-Bar Meirav, Dujovny Tal, Vlodavsky Eugene, Postovsky Sergey, Morgenstern Sara, Braslavsky Diana, Nissan Aviram, Steinberg Ran, Feinmesser Meora
1 Department of Pathology, Rabin Medical Center, Petach Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
2 Department of Pediatric Hematology and Oncology, Rambam Medical Center, Haifa, Israel.
Pediatr Dev Pathol. 2015 Jul-Aug;18(4):327-30. doi: 10.2350/14-06-1511-CR.1. Epub 2015 Apr 9.
Malignant mesothelioma is an uncommon tumor that usually arises in the pleural cavity of adults with a history of asbestos exposure. Less frequently, it appears in the peritoneum or other mesothelial surfaces. Deciduoid mesothelioma is a rare subtype that has been found at both sites. Of the 3 reported cases in children, 2 originated in the mesenterium and 1 in the pleura. We describe a 4th case of pediatric, malignant, deciduoid mesothelioma and a third case in the mesenteric cavity. The patient was an 8-year-old girl who presented with abdominal pain and fullness. Workup revealed extensive involvement of the abdomen by a serosa-based tumor. The clinical and pathologic findings are described, and the pertinent literature is reviewed.
恶性间皮瘤是一种罕见肿瘤，通常发生于有石棉接触史的成人胸膜腔。较少情况下，见于腹膜或其他间皮表面。蜕膜样间皮瘤是一种罕见的亚型，已在上述两个部位发现。在已报道的3例儿童病例中，2例起源于肠系膜，1例起源于胸膜。我们描述了第4例儿童恶性蜕膜样间皮瘤，也是肠系膜腔的第3例病例。患者为一名8岁女孩，表现为腹痛和腹胀。检查发现一个以浆膜为基础的肿瘤广泛累及腹部。描述了临床和病理表现，并复习了相关文献。
