De Jesús-Berrios Yohana, Santos-Rodríguez Ruth A, Dexter Donald, Nieves-Plaza Mariely, Nazario Cruz M
P R Health Sci J. 2015 Mar;34(1):14-9.
Breathlessness is a common and disabling symptom of pulmonary disease. Measuring its severity is recommended as such measurements can be helpful in both clinical and research settings. The oxygen-cost diagram (OCD) and the Medical Research Council (MRC) dyspnea scale were developed in English to measure severity of dyspnea. These scales were previously translated to Spanish and adapted for use in a Hispanic population. The objective of this study is to assess the psychometric properties of these scales. We propose the scales correlate well with measures of physiological impairment.
Subjects having pulmonary disease rated their perceptions of dyspnea using the scales, performed a spirometry test, and did a 6-min walk. Spearman correlation coefficients (p) were used to correlate dyspnea scores with spirometric parameters and distance walked (6MWD).
Sixty-six patients having stable asthma (n = 36), chronic obstructive pulmonary disease (n = 19), or interstitial lung disease (n = 11) participated in the study. OCD scores showed a significant correlation with FEV1 (p = 0.41; p < 0.01), FEV1% (p = 0.36; p < 0.01), FVC (p = 0.44; p < 0.01), and FVC% (p = 0.37; p < 0.01) in the study population. The OCD scores were highly correlated with 6MWD (p = 0.59, p < 0.01). The MRC dyspnea scale showed significant inverse correlation with FEV1 (p = -0.34; p < 0.01) and 6MWD (p = -0.33; p < 0.05), but the correlations were weaker compared to the correlations with the OCD scale.
The severity of breathlessness as measured by the adapted Spanish OCD showed a moderate to high correlation with spirometric parameters and 6MWD; therefore, the adapted OCD should prove to be useful in Puerto Rico.
呼吸急促是肺部疾病常见且使人丧失活动能力的症状。建议对其严重程度进行测量，因为此类测量在临床和研究环境中均可能有所帮助。氧耗图（OCD）和医学研究委员会（MRC）呼吸困难量表是用英文开发的，用于测量呼吸困难的严重程度。这些量表先前已被翻译成西班牙语并适用于西班牙裔人群。本研究的目的是评估这些量表的心理测量特性。我们认为这些量表与生理损伤指标具有良好的相关性。
患有肺部疾病的受试者使用这些量表对其呼吸困难感受进行评分，进行肺功能测试，并进行6分钟步行测试。使用Spearman相关系数（p）将呼吸困难评分与肺功能参数和步行距离（6MWD）进行相关性分析。
66例患有稳定型哮喘（n = 36）、慢性阻塞性肺疾病（n = 19）或间质性肺疾病（n = 11）的患者参与了本研究。在研究人群中，OCD评分与FEV1（p = 0.41；p < 0.01）、FEV1%（p = 0.36；p < 0.01）、FVC（p = 0.44；p < 0.01）和FVC%（p = 0.37；p < 0.01）显著相关。OCD评分与6MWD高度相关（p = 0.59，p < 0.01）。MRC呼吸困难量表与FEV1（p = -0.34；p < 0.01）和6MWD（p = -0.33；p < 0.05）呈显著负相关，但与OCD量表的相关性相比，其相关性较弱。
经改编的西班牙语OCD所测量的呼吸急促严重程度与肺功能参数和6MWD呈中度至高度相关；因此，经改编的OCD在波多黎各应被证明是有用的。
