Alayeto Ortega Jose, Alier Fabregó Albert, Puig Verdie Lluis, Sorli Redo Maria Luisa, Horcajada Gallego Juan Pablo, Portillo Bordonabe M Eugenia
Servicio de Microbiología, Hospital Sant Joan de Déu, Barcelona, España.
Servicio de Cirugía Ortopédica y Traumatología, Hospital del Mar, Barcelona, España.
Rev Iberoam Micol. 2015 Oct-Dec;32(4):265-8. doi: 10.1016/j.riam.2014.10.004. Epub 2015 Feb 26.
From the available literature, it is demonstrated that dematiaceous fungal infections mostly affect immunosuppressed patients. These infections can occur in different forms, from subcutaneous infection to disseminated forms that may compromise the life of the patient. In many cases the infection is related to the inoculation of the microorganism by diverse traumatic mechanisms, which determines the course of the infection to be slower in some cases.
We describe two cases of phaeohyphomycosis caused by Phaeoacremonium parasiticum: A cancer patient with subcutaneous lesions affecting the left hand and forearm, and a patient who presented with subcutaneous abscesses in the left leg.
These cases confirm the presence of this type of fungus in Spain. In the second case a combination of amphotericin B lipid complex and posaconazole, together with several surgical resections, were necessary in order to overcome the infection.
从现有文献可知，暗色丝孢菌感染主要影响免疫抑制患者。这些感染可呈现不同形式，从皮下感染到可能危及患者生命的播散性形式。在许多情况下，感染与微生物通过多种创伤机制接种有关，这决定了在某些情况下感染进程较慢。
我们描述了两例由寄生拟茎点霉引起的暗色丝孢霉病病例：一例癌症患者左手和前臂出现皮下病变，另一例患者左腿出现皮下脓肿。
这些病例证实了西班牙存在这种真菌。在第二例病例中，为了战胜感染，必须联合使用两性霉素B脂质体复合物和泊沙康唑，并进行多次手术切除。
