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由……引起的皮下暗色丝孢霉病:哥斯达黎加的首例临床病例报告

Subcutaneous phaeohyphomycosis due to : The first clinical case report in Costa Rica.

作者信息

Cob Mariamalia, López Luisa F, Sexton D Joseph, Fallas Adrián, Muñoz Juan David, Gutiérrez Ricardo

机构信息

Medical Mycology Laboratory, Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud, Cartago, Costa Rica.

Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, USA.

出版信息

Med Mycol Case Rep. 2024 Apr 27;44:100650. doi: 10.1016/j.mmcr.2024.100650. eCollection 2024 Jun.

Abstract

is a genus of dematiaceous fungi that rarely causes human infections. We describe a case of subcutaneous infection in a 70-year-old diabetic man with lesions on the dorsum of the one foot. The agent was isolated, and for the final identification we performed matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and DNA sequencing. After diagnosis, the patient underwent curettage of the cyst and received 100mg of Itraconazole, twice daily for 6 months. Clinical resolution of the lesion was observed after treatment. This is the first case of infection by reported in Costa Rica.

摘要

是一组暗色真菌,很少引起人类感染。我们描述了一例70岁糖尿病男性足部背部出现病变的皮下感染病例。分离出病原体后,为进行最终鉴定,我们进行了基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)和DNA测序。诊断后,患者接受了囊肿刮除术,并接受每日两次、每次100mg伊曲康唑治疗,持续6个月。治疗后观察到病变临床消退。这是哥斯达黎加报告的首例由 引起的感染病例。

原文中“is a genus of dematiaceous fungi that rarely causes human infections.”和“reported in Costa Rica.”处有信息缺失,翻译时保留了原文的不完整性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/593d/11070910/bb2fa3621e22/gr1.jpg

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