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[果糖-1,6-二磷酸对大鼠实验性心肌梗死坏死面积大小及急性期病程的影响]

[Effect of fructose-1,6-diphosphate on the size of the necrotic area and course of the acute period of experimental myocardial infarction in rats].

作者信息

Sernov L N, Snegireva G V, Gatsura V V

出版信息

Kardiologiia. 1989 Aug;29(8):66-9.

PMID:2585964
Abstract

The experiments on rats indicated that fructose-1,6-diphosphate substantially decreased the sizes of a necrotic zone, elevated myocardial ATP levels, reduced the edematization of lung tissue, shortened the duration of early postocclusive arrhythmias, and increased the latent period for their development. A dose-dependent cardioprotective effect was found in the preparation.

摘要

对大鼠的实验表明,1,6-二磷酸果糖可显著减小坏死区大小,提高心肌ATP水平,减轻肺组织水肿,缩短闭塞后早期心律失常的持续时间,并延长其发生的潜伏期。该制剂具有剂量依赖性心脏保护作用。

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