Mit'kov V V, Ogneva T V, Goriaĭnova I I, Milanov S, Milkov V
Med Radiol (Mosk). 1989 Nov;34(11):22-4.
The results of comparative investigation of 266 cancer patients, 44 patients with benign G. I. tract diseases and 66 healthy subjects using 2 tumor markers (CEA and Ca-19-9) showed the diagnostic value of both methods, not exceeding 38-42%. The most informative were the data on patients with pancreatic and colorectal cancers as well as in patients with detected metastases. Significant differences in the sensitivity, specificity and diagnostic informative value between the two markers were undetectable.
对266例癌症患者、44例胃肠道良性疾病患者和66名健康受试者使用两种肿瘤标志物(癌胚抗原和糖类抗原19-9)进行比较研究的结果表明,两种方法的诊断价值均不超过38%-42%。最具信息量的数据来自胰腺癌和结直肠癌患者以及检测到转移的患者。两种标志物在敏感性、特异性和诊断信息量方面未发现显著差异。