Kim Yong Kwan, Lim Seong-In, Lim Ji-Ae, Cho In-Soo, Park Eun-Hye, Le Van Phan, Hien Nguyen Ba, Thach Pham Ngoc, Quynh Do Hai, Vui Tran Quang, Tien Nguyen Trung, An Dong-Jun
Animal and Plant Quarantine Agency, Anyang, Gyeonggi-do, 430-824, Republic of Korea.
Arch Virol. 2015 Jun;160(6):1573-7. doi: 10.1007/s00705-015-2411-5. Epub 2015 Apr 12.
Porcine epidemic diarrhea virus (PEDV) causes severe diarrhea and dehydration in suckling pigs and has caused high rates of death among piglets and substantial economic loss in Vietnam since 2009. To investigate the genotypes of prevailing PEDVs, intestinal and fecal samples from piglets from central and northern Vietnam were collected and analyzed. Phylogenetic analysis of the nucleotide sequences of complete spike genes of PEDVs from Vietnam resulted in the identification of two divergent groups. PEDVs (HUA-PED45 and HUA-PED47) belonged to the G2b group, along with Chinese, US, and Korean strains occurring at the end of 2010, in May 2013 and in November 2013, respectively. Six strains from the Quang Tri region were assigned to the G1b group, along with Chinese and US strains. The Vietnamese PEDVs detected in infected piglets had a nationwide distribution and belonged to the G2b and G1b genotypes.
猪流行性腹泻病毒（PEDV）可导致哺乳仔猪严重腹泻和脱水，自2009年以来已在越南造成仔猪高死亡率和巨大经济损失。为调查流行的PEDV基因型，收集并分析了越南中部和北部仔猪的肠道和粪便样本。对越南PEDV完整刺突基因的核苷酸序列进行系统发育分析，结果鉴定出两个不同的组。PEDV（HUA-PED45和HUA-PED47）属于G2b组，分别与2010年底、2013年5月和2013年11月出现的中国、美国和韩国毒株同属一组。来自广治省地区的6个毒株与中国和美国的毒株一起被归为G1b组。在受感染仔猪中检测到的越南PEDV在全国范围内分布，属于G2b和G1b基因型。
