A型主动脉夹层幸存者的长期预后和生活质量
Long-Term Outcome and Quality of Life in Aortic Type A Dissection Survivors.
作者信息
Endlich Matthias, Hamiko Marwan, Gestrich Christopher, Probst Chris, Mellert Fritz, Winkler Kai, Welz Armin, Schiller Wolfgang
机构信息
Department of Cardiovascular Surgery, University Hospital Bonn, Bonn, Germany.
出版信息
Thorac Cardiovasc Surg. 2016 Mar;64(2):91-9. doi: 10.1055/s-0035-1548734. Epub 2015 Apr 10.
BACKGROUND
Aortic dissection is a severe and sophisticated disease that is often linked with a number of possible complications. Our study concerns with long-term outcome and quality of life (QoL) in acute aortic dissection type A (AADA) survivors.
METHODS
From January 1999 until December 2006, 120 consecutive patients with AADA received an emergency operation. Of the total number of patients, 84 were males (70.0%) and 36 females (30.0%), mean aged 59.8 ± 12 years with a mean follow-up (FU) of 99.2 ± 6 months.
RESULTS
Overall mortality was 39.1% during the observational period with a maximum of 156 months. SF-36 observation showed a significant decay in both Physical Component Summary (PCS) and Mental Component Summary (MCS) in FUII (PCS = 38.4) versus FUI (PCS = 43.4, p = 0.013).
CONCLUSION
With ongoing postoperative time, patients did not recover but instead have got worse in terms of QoL. The decrease in MCP and linked subscores is an underestimated factor in QoL and long-term outcome after AADA. This is especially true in younger patients, which are judged to compensate better than older patients.
背景
主动脉夹层是一种严重且复杂的疾病，常伴有多种可能的并发症。我们的研究关注急性A型主动脉夹层（AADA）幸存者的长期预后和生活质量（QoL）。
方法
从1999年1月至2006年12月，120例连续的AADA患者接受了急诊手术。在所有患者中，男性84例（70.0%），女性36例（30.0%），平均年龄59.8±12岁，平均随访（FU）99.2±6个月。
结果
在长达156个月的观察期内，总死亡率为39.1%。SF - 36观察显示，与随访I期（PCS = 43.4，p = 0.013）相比，随访II期（PCS = 38.4）的身体成分总结（PCS）和心理成分总结（MCS）均显著下降。
结论
随着术后时间的推移，患者并未康复，反而在生活质量方面有所恶化。MCP及其相关子分数的下降是AADA后生活质量和长期预后中一个被低估的因素。在年轻患者中尤其如此，他们被认为比老年患者恢复得更好。
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