Aix Marseille Université, INS, UMR_S 1106, 13005, Marseille, France.
Inserm, UMR_S 1106, 13005, Marseille, France.
Adv Mater. 2015 May 27;27(20):3138-44. doi: 10.1002/adma.201500482. Epub 2015 Apr 11.
In treating epilepsy, the ideal solution is to act at a seizure's onset, but only in the affected regions of the brain. Here, an organic electronic ion pump is demonstrated, which directly delivers on-demand pure molecules to specific brain regions. State-of-the-art organic devices and classical pharmacology are combined to control pathological activity in vitro, and the results are verified with electrophysiological recordings.
在治疗癫痫时，理想的解决方案是在癫痫发作时立即采取行动，但只能在大脑受影响的区域进行。在这里，展示了一种有机电子离子泵，它可以直接按需将纯分子递送到特定的大脑区域。该设备结合了最先进的有机器件和经典药理学，以控制体外的病理性活动，并通过电生理记录验证了结果。
