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免疫功能正常宿主原发性皮肤毛霉病一例的成功管理

Successful management of a case of primary cutaneous mucormycosis in an immunocompetent host.

作者信息

Sagar Sushma, Kumar Subodh, Gupta Amit, Singhal Maneesh, Mishra Biplab

机构信息

the Jai Prakash Narayan Apex Trauma Center, All India Institute of Medical Sciences, New Delhi, India.

the Jai Prakash Narayan Apex Trauma Center, All India Institute of Medical Sciences, New Delhi, India; email:

出版信息

Wounds. 2013 May;25(5):136-40.

Abstract

Primary cutaneous mucormycosis is a rare disease in the immunocompetent, and research on this condition is limited to case reports. Clinical presentation is not sufficiently distinctive to allow a diagnosis and the immunocompetent state precludes even the suspicion of the condition. There is agreement in literature regarding the absence of guidelines for its treatment. Most reports have used a combination of aggressive and repeated surgical debridement and systemic antifungals, usually amphotericin B. The authors propose the use of vacuumassisted closure technology in managing these wounds with a possible role in decreasing the number and extent of debridement and limiting deeper tissue damage. .

摘要

原发性皮肤毛霉病在免疫功能正常者中是一种罕见疾病,对此病症的研究仅限于病例报告。其临床表现没有足够的特异性来确诊,且免疫功能正常状态甚至会排除对该病的怀疑。文献中对于其治疗缺乏指南这一点存在共识。大多数报告采用了积极且反复的手术清创与全身性抗真菌药物联合使用的方法,通常使用两性霉素B。作者提议在处理这些伤口时使用负压封闭引流技术,其可能在减少清创的次数和范围以及限制深层组织损伤方面发挥作用。

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