Ruan Z S, Li T, Ren R R, Zhao Y, Li K, Mao Y F, Shen G, Jiang L
Department of Anesthesiology and Surgical Intensive Care Unit, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
State Key laboratory of Electronic Thin Films and Integrated Devices and Biomedical Engineering Department, University of Electronic Science & Technology, Chengdu, China.
Genet Mol Res. 2015 Mar 31;14(1):2920-8. doi: 10.4238/2015.March.31.23.
Central venous blood oxygen saturation (ScvO2) is an important monitoring index of fluid resuscitation. However, monitoring of ScvO2 is not continuous and invasive. Near infrared spectroscopy (NIRS) is an optical technology for the noninvasive detection of hemodynamic changes, with advantages of being real-time, continuous, low-cost, and portable. The present study aimed to determine whether a correlation exists between the tissue blood oxygen saturation in the internal jugular venous area (StO2) data obtained with NIRS and the ScvO2 and whether these two quantities are equivalent. Data were collected from 13 patients. We used ultrasound to locate the placement site for the NIRS light source outside the internal jugular vein. Meanwhile, a sample for blood gas analysis was obtained through the central venous catheter. A correlation analysis between the StO2 and ScvO2 of 13 samples was performed (Pearson correlation coefficient), suggesting a high correlation between them (r = 0.906, StO2 =1.0018 ScvO2 +2.8524). Bland-Altman analysis was also performed between the StO2 and ScvO2. Results were as follows: 100% of monitored points fell within the range of the mean ± 1.96 SD of the difference between the StO2 and ScvO2; range of the mean ± 1.96 SD of the difference between the StO2 and ScvO2 was 3 ± 10.2; confidence interval of the difference between the StO2 and ScvO2 was -7.2 to 13.2%. The StO2 monitored with NIRS correlated highly with the ScvO2 measured in the internal jugular vein. Therefore, the StO2 can be used for directing clinical treatment with further research.
中心静脉血氧饱和度（ScvO2）是液体复苏的重要监测指标。然而，ScvO2的监测不连续且具有侵入性。近红外光谱技术（NIRS）是一种用于无创检测血流动力学变化的光学技术，具有实时、连续、低成本和便携的优点。本研究旨在确定通过NIRS获得的颈内静脉区域组织血氧饱和度（StO2）数据与ScvO2之间是否存在相关性，以及这两个量是否等效。收集了13例患者的数据。我们使用超声定位颈内静脉外侧NIRS光源的放置位置。同时，通过中心静脉导管获取用于血气分析的样本。对13个样本的StO2和ScvO2进行相关性分析（Pearson相关系数），结果表明它们之间具有高度相关性（r = 0.906，StO2 = 1.0018ScvO2 + 2.8524）。还对StO2和ScvO2进行了Bland-Altman分析。结果如下：100%的监测点落在StO2与ScvO2差值均值±1.96标准差的范围内；StO2与ScvO2差值均值±1.96标准差的范围为3±10.2；StO2与ScvO2差值的置信区间为-7.2%至13.2%。通过NIRS监测的StO2与颈内静脉测量的ScvO2高度相关。因此，StO2可用于指导临床治疗，有待进一步研究。
