内质网-叶绿体膜接触位点的脂质转运。

Lipid trafficking at endoplasmic reticulum-chloroplast membrane contact sites.

机构信息

Laboratoire de Physiologie Cellulaire et Végétale, Unité Mixte Recherche 5168, Centre National Recherche Scientifique, Université de Grenoble-Alpes, Institut National de la Recherche Agronomique, Commissariat à l'Energie Atomique et Energies Alternatives, Institut de Recherches en Technologies et Sciences pour le Vivant, 17 Avenue des Martyrs, F-38054 Grenoble, France.

出版信息

Curr Opin Cell Biol. 2015 Aug;35:21-9. doi: 10.1016/j.ceb.2015.03.004. Epub 2015 Apr 8.

DOI:10.1016/j.ceb.2015.03.004

PMID:25868077

Abstract

Glycerolipid synthesis in plant cells is characterized by an intense trafficking of lipids between the endoplasmic reticulum (ER) and chloroplasts. Initially, fatty acids are synthesized within chloroplasts and are exported to the ER where they are used to build up phospholipids and triacylglycerol. Ultimately, derivatives of these phospholipids return to chloroplasts to form galactolipids, monogalactosyldiacylglycerol and digalactosyldiacylglycerol, the main and essential lipids of photosynthetic membranes. Lipid trafficking was proposed to transit through membrane contact sites (MCSs) connecting both organelles. Here, we review recent insights into ER-chloroplast MCSs and lipid trafficking between chloroplasts and the ER.

摘要

植物细胞中的甘油脂质合成的特点是内质网 (ER) 和叶绿体之间脂质的强烈运输。最初，脂肪酸在叶绿体中合成，并被输出到 ER，在那里它们被用来构建磷脂和三酰基甘油。最终，这些磷脂的衍生物返回叶绿体形成半乳糖脂、单半乳糖二酰甘油和双半乳糖二酰甘油，这是光合膜的主要和必需脂质。脂质运输被认为是通过连接两个细胞器的膜接触位点 (MCS) 进行的。在这里，我们回顾了最近关于 ER-叶绿体 MCS 和叶绿体与 ER 之间脂质运输的研究进展。