Xie Guangyou, Lu Furong, Yang Haitao
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2014 Dec;31(6):1419-22.
Low back pain caused by intervertebral disc degeneration is a common clinical chronic disease. The regenerative ability of intervertebral disc tissue is extremely poor. Meanwhile, current treating methods can not fundamentally solve such problems. With the increasing awareness of the mechanism of disc degeneration and the rapid development of the fields of cellular and molecular biology, gene and materials engineering, using stem cells and tissue engineering technology to slow down or reverse the progress of disc degeneration may become possible. The author reviewed the application of stem cells for treating degenerative discs from present researching status and concepts for the future in the combination of researches reported both at home and abroad.
椎间盘退变引起的下腰痛是一种常见的临床慢性疾病。椎间盘组织的再生能力极差。同时，目前的治疗方法无法从根本上解决此类问题。随着对椎间盘退变机制认识的不断提高以及细胞与分子生物学、基因与材料工程领域的快速发展，利用干细胞和组织工程技术减缓或逆转椎间盘退变的进程或许成为可能。作者结合国内外报道的研究，从目前的研究现状及未来理念方面综述了干细胞在治疗退变椎间盘方面的应用。
