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经皮内镜下胃造口术患儿并发症的危险因素。

Risk factors for complications in infants and children with percutaneous endoscopic gastrostomy tubes.

作者信息

McSweeney Maireade E, Kerr Jessica, Jiang Hongyu, Lightdale Jenifer R

机构信息

Division of Gastroenterology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.

Division of Gastroenterology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.

出版信息

J Pediatr. 2015 Jun;166(6):1514-9.e1. doi: 10.1016/j.jpeds.2015.03.009. Epub 2015 Apr 11.

Abstract

OBJECTIVE

To identify risk factors associated with percutaneous endoscopic gastrostomy (PEG) tube complications in a large cohort of infants and children.

STUDY DESIGN

We performed a chart review of 591 pediatric patients undergoing PEG tube placement between 2006 and 2010 at Boston Children's Hospital. Frequency and type of major and minor complications associated with PEG tubes in children were identified. Univariate and multivariate analyses were then conducted to determine potential risk factors for complications.

RESULTS

A total of 198 PEG-related complications (72 major and 126 minor) were noted in our cohort of 591 patients. Approximately 10.5% of patients experienced at least one major complication and 16.4% experienced at least one minor complication, with the great majority of complications occurring after discharge postplacement. Age <6 months (P = .003), American Society of Anesthesiologists class III (P = .02), and presence of a neurologic disorder (P = .05) were found to be protective against experiencing a major complication, whereas the presence of a ventriculoperitoneal shunt was confirmed to be a risk factor (P = .01) for major complications.

CONCLUSION

Both minor and major complications are common in children after PEG tube placement, with most complications occurring several months postoperatively. Certain patient factors, including age, neurologic status, and American Society of Anesthesiologists class, may be protective, and the presence of a ventriculoperitoneal shunt may be associate with an increased risk of complications after PEG tube placement.

摘要

目的

确定一大群婴幼儿经皮内镜下胃造口术(PEG)管并发症的相关危险因素。

研究设计

我们对2006年至2010年在波士顿儿童医院接受PEG管置入的591例儿科患者的病历进行了回顾。确定了儿童PEG管相关的主要和次要并发症的频率及类型。然后进行单因素和多因素分析以确定并发症的潜在危险因素。

结果

在我们的591例患者队列中,共记录了198例与PEG相关的并发症(72例主要并发症和126例次要并发症)。约10.5%的患者经历了至少一种主要并发症,16.4%的患者经历了至少一种次要并发症,绝大多数并发症发生在置管后出院期间。发现年龄<6个月(P = 0.003)、美国麻醉医师协会Ⅲ级(P = 0.02)和存在神经系统疾病(P = 0.05)可预防主要并发症的发生,而脑室腹腔分流的存在被确认为主要并发症的危险因素(P = 0.01)。

结论

PEG管置入术后儿童的主要和次要并发症均很常见,大多数并发症发生在术后数月。某些患者因素,包括年龄、神经状态和美国麻醉医师协会分级,可能具有保护作用,而脑室腹腔分流的存在可能与PEG管置入术后并发症风险增加相关。

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