Jean-Bart C Charlotte, Aumar Madeleine, Ley Delphine, Antoine Matthieu, Cailliau Emeline, Coopman Stéphanie, Guimber Dominique, Ganga Serge, Turck Dominique, Gottrand Frédéric
Department of Pediatric Gastroenterology, Hepatology, and Nutrition, CHU Lille, INSERM 1286, University of Lille, Lille, 59000, France.
Department of Pediatrics, Children's Hospital, Roubaix, France.
Eur J Pediatr. 2023 Apr;182(4):1665-1672. doi: 10.1007/s00431-023-04822-7. Epub 2023 Feb 3.
To assess the complications of one-step button percutaneous endoscopic gastrostomy (B-PEG) and determine risk factors for developing stomal infections or gastropexy complications. A retrospective study of 679 children who underwent a B-PEG procedure in a single tertiary care center over a 10-year period to December 2020 was conducted. Patient characteristics, early complications (occurring ≤ 7 days after the procedure), late complications (> 7 days after the procedure), and outcomes were collected from medical records. A list of potential risk factors, including age at procedure, prematurity, underlying neurological disease, and undernutrition, was determined a priori. At least 1 year of follow-up was available for 513 patients. Median follow-up duration was 2.8 years (interquartile range 1.0-4.9 years). Major complications were rare (< 2%), and no death was related to B-PEG. Early complications affected 15.9% of the study population, and 78.0% of children presented late complications. Development of granulation tissue was the most common complication followed in frequency by tube dislodgment and T-fastener complications. Only 24 patients (3.5%) presented stomal infections. Young age at the time of PEG placement (odds ratio (OR) 2.34 [1.03-5.30], p = .042) was a risk factor for developing peristomal infection. T-fastener migration occurred in 17.3% of children, and we found underlying neurological disease was a protective factor (OR 0.59 [0.37-0.92], p = .019). Conclusion: B-PEG is a safe method and associated with a low rate of local infection. However, T-fasteners are associated with significant morbidity and require particular attention in young and premature infants. What is Known: • Percutaneous endoscopic gastrostomy (PEG) is the preferred method to provide long-term enteral nutrition in children to prevent malnutrition. The Pull-PEG method is still the most commonly used with complications , such as stomal infection. Since its description, only a few studies have reported postoperative complications of one-step button PEG (B-PEG). What is New: • T-fastener complications were not rare, and underlying neurologic disease was a protective factor. A very low rate of stomal infection was described, and young age at the time of PEG placement was a risk factor. The B-PEG is a safe method with fewer major complications than P-PEG in children.
评估一步式纽扣型经皮内镜下胃造口术(B-PEG)的并发症,并确定发生造口感染或胃固定术并发症的危险因素。对一家三级医疗中心在10年期间(至2020年12月)接受B-PEG手术的679例儿童进行了一项回顾性研究。从病历中收集患者特征、早期并发症(术后≤7天发生)、晚期并发症(术后>7天发生)及预后情况。预先确定了一系列潜在危险因素,包括手术时年龄、早产、潜在神经疾病和营养不良。513例患者至少有1年的随访资料。中位随访时间为2.8年(四分位间距1.0 - 4.9年)。严重并发症罕见(<2%),且无死亡与B-PEG相关。早期并发症影响了15.9%的研究人群,78.0%的儿童出现晚期并发症。肉芽组织形成是最常见的并发症,其次是导管移位和T型钉并发症。仅24例患者(3.5%)出现造口感染。PEG放置时年龄较小(比值比(OR)2.34 [1.03 - 5.30],p = 0.042)是发生造口周围感染的危险因素。17.3%的儿童发生T型钉移位,我们发现潜在神经疾病是一个保护因素(OR 0.59 [0.37 - 0.92],p = 0.019)。结论:B-PEG是一种安全的方法,局部感染率低。然而,T型钉与显著的发病率相关,在幼儿和早产儿中需要特别关注。已知信息:• 经皮内镜下胃造口术(PEG)是为预防儿童营养不良提供长期肠内营养的首选方法。牵拉式PEG方法仍是最常用的方法,但存在造口感染等并发症。自其被描述以来,仅有少数研究报道了一步式纽扣型PEG(B-PEG)的术后并发症。新发现:• T型钉并发症并不罕见,潜在神经疾病是一个保护因素。报道了非常低的造口感染率,PEG放置时年龄较小是一个危险因素。在儿童中,B-PEG是一种安全的方法,严重并发症比P-PEG少。