BCG 导致的感染性心内膜炎病例。

A case of infectious endocarditis due to BCG.

机构信息

Pôle de Maladies Infectieuses, Hôpital de la Timone, Marseille, France.

Pôle de Maladies Infectieuses, Hôpital de la Timone, Marseille, France; Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UM 63, UMR CNRS 7278, IRD 198, Inserm 1095, Aix-Marseille Université, Faculté de Médecine, 27 Boulevard Jean Moulin, 13385 Marseille cedex 05, France.

出版信息

Int J Infect Dis. 2015 Jun;35:27-8. doi: 10.1016/j.ijid.2015.04.003. Epub 2015 Apr 11.

DOI:10.1016/j.ijid.2015.04.003

PMID:25869076

Abstract

The occurrence of bacillus Calmette-Guérin (BCG) disease following instillation for bladder cancer is commonly documented. The intravesical administration of BCG is generally safe, but may present severe complications. A fatal case of native aortic valve infectious endocarditis with septicemia due to BCG in a patient treated with intravesical instillation is reported herein.

摘要

文献报道膀胱癌患者经膀胱内灌注卡介苗（BCG）后可发生卡介苗病。一般认为BCG 膀胱内灌注是安全的，但也可能出现严重并发症。本文报告 1 例因膀胱内灌注而发生的致命性细菌性心内膜炎合并败血症，感染源为 BCG，感染部位为自体主动脉瓣。