Beware of Drug Interactions Treating Iatrogenic Endocarditis from Intravesical BCG Instillation.
作者信息
Curri Francesca, Da Porto Andrea, Casarsa Viviana, Albini Daria, Minen Giorgio, Sechi Leonardo A
机构信息
Department of Experimental and Clinical Medical Sciences, Clinica Medica, University Hospital, University of Udine, Udine, Italy.
Department of Cardiac Sciences, Cardiology, University Hospital, University of Udine, Udine, Italy.
出版信息
Eur J Case Rep Intern Med. 2021 Feb 1;8(3):002263. doi: 10.12890/2021_002263. eCollection 2021.
UNLABELLED
We report a case of mechanical mitral valve endocarditis associated with miliary disseminated bacillus Calmette-Guerin (BCG) infection following intravesical instillations for minimally invasive bladder cancer in a 65-year-old man. The diagnosis was established by echocardiographic evidence of vegetation on the prosthetic mitral valve, miliary lesions in the lungs and evidence of bloodstream infection sustained by . We successfully treated the patient with the classical regimen of quadruple antituberculous therapy.
LEARNING POINTS
To consider endocarditis as an extra-pulmonary manifestation of infection, especially in the presence of predisposing heart conditions and risk factors.To be careful of drug interactions among warfarin, rifampin and amiodarone.
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