Miura Hajime, Takahashi Yoshinori, Maki Yukimi, Sugino Megumi
Laboratory for Applied Physiology, Institute of Socio-Arts and Sciences, Tokushima University, 1-1 Minamijyosanjima, Tokushima, 7708502, Japan,
Eur J Appl Physiol. 2015 Sep;115(9):1847-54. doi: 10.1007/s00421-015-3168-y. Epub 2015 Apr 14.
Regular physical exercise is recommended for the prevention and treatment of cardiovascular disease. However, it is unclear whether the effects of exercise training on arterial stiffness are the same in older hypertensive individuals as those observed in older healthy subjects. The aim of this study was to compare the effects of exercise training on arterial stiffness between older hypertensive and healthy females.
Ninety-two females with untreated hypertension and 108 healthy females were randomly assigned to either the control group or to participate in a 12-week training program. In the training groups, the subjects engaged in 90 min of training twice a week for 12 weeks. Each training program included recreational activities, six to eight resistance exercises for circuit training and chair-based exercise for the lower extremities. The systolic/diastolic blood pressure (SBP/DBP) and brachial to ankle pulse wave velocity (baPWV) were obtained in the supine position using an automatic pulse wave form analyzer.
Compared with that observed in the control group, greater reductions in the baPWV and SBP/DBP were achieved in both training groups (P < 0.05). Furthermore, a significant difference in the delta baPWV values obtained before and after training was noted between the hypertensive (-72.5 ± 8.1 cm s(-1)) and healthy females (-131.5 ± 107.3 cm s(-1)) who participated in the training program (P < 0.05).
These data indicate that exercise training produces fewer improvements in arterial stiffness in older hypertensive females than in older healthy females.
推荐进行规律的体育锻炼以预防和治疗心血管疾病。然而,运动训练对动脉僵硬度的影响在老年高血压个体中是否与在老年健康受试者中观察到的相同尚不清楚。本研究的目的是比较运动训练对老年高血压女性和健康女性动脉僵硬度的影响。
92名未经治疗的高血压女性和108名健康女性被随机分配到对照组或参与一个为期12周的训练项目。在训练组中,受试者每周进行两次90分钟的训练,持续12周。每个训练项目包括娱乐活动、六到八项用于循环训练的抗阻运动以及针对下肢的椅上运动。使用自动脉搏波形分析仪在仰卧位测量收缩压/舒张压(SBP/DBP)和臂踝脉搏波速度(baPWV)。
与对照组相比,两个训练组的baPWV和SBP/DBP均有更大程度的降低(P < 0.05)。此外,参与训练项目的高血压女性(-72.5 ± 8.1 cm s(-1))和健康女性(-131.5 ± 107.3 cm s(-1))在训练前后的baPWV差值存在显著差异(P < 0.05)。
这些数据表明,运动训练对老年高血压女性动脉僵硬度的改善作用小于老年健康女性。