Babik Jennifer M, Chin-Hong Peter
Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA,
Curr Infect Dis Rep. 2015 Apr;17(4):473. doi: 10.1007/s11908-015-0473-x.
Transplant tourism is commonly defined as travel abroad for the purpose of transplantation, but the term evokes ethical and legal concerns about commercial transplantation. Due to the mismatch in supply and demand for organs, transplant tourism has increased over the last several decades and now accounts for 10 % of transplants worldwide. Patients from the USA who pursue transplantation abroad do so most commonly for renal transplantation, and travel mostly to China, the Philippines, and India. Transplant tourism puts the organ recipient at risk for surgical complications, poor graft outcome, increased mortality, and a variety of infectious complications. Bacterial, viral, fungal, and parasitic infections have all been described, and most concerning are the high rates of blood-borne viral infections and invasive, often fatal, fungal infections. Transplant and infectious diseases physicians should have a high degree of suspicion for infectious complications in patients returning from transplantation abroad.
移植旅游通常被定义为出于移植目的而出国旅行,但这个术语引发了对商业移植的伦理和法律担忧。由于器官供需不匹配,在过去几十年里移植旅游有所增加,目前占全球移植手术的10%。在美国,到国外寻求移植的患者最常进行的是肾移植,主要前往中国、菲律宾和印度。移植旅游使器官接受者面临手术并发症、移植效果不佳、死亡率增加以及各种感染并发症的风险。细菌、病毒、真菌和寄生虫感染均有报道,最令人担忧的是血源性病毒感染率高以及侵袭性、往往致命的真菌感染。移植科和传染病科医生应对从国外移植归来的患者的感染并发症保持高度怀疑。