Neupane Ritesh, Taweesedt Pahnwat Tonya, Anjum Humayun, Surani Salim
Department of Medicine, Penn State Health Milton S Hershey Medical Center, Hershey, PA 17033, United States.
Department of Medicine, Corpus Christi Medical Center, Corpus Christi, TX 78412, United States.
World J Hepatol. 2021 Jul 27;13(7):717-722. doi: 10.4254/wjh.v13.i7.717.
Liver transplant has been shown to significantly improve mortality and quality of life in various liver diseases such as acute liver failure, end-stage liver disease, and liver cancer. While the organ transplant demand is continuing to rise, the organ donation supply remains unmatched. The organ shortage, high cost, and long waiting lists have stimulated a desire for routes that may be unethical. This process which is named transplant tourism is the term used to describe traveling to another country to purchase an organ for transplant. Liver transplant tourism has been associated with post-transplant complications and higher mortality compared to a domestic liver transplant. Improper pre-and post-transplant infectious screening, inadequate opportunistic infection prophylaxis, and loss to follow-up were noted in patients who travel abroad for a liver transplant. It is crucial to understand the risk of transplant tourism to prevent morbidity and mortality.
肝移植已被证明能显著提高各种肝脏疾病(如急性肝衰竭、终末期肝病和肝癌)患者的死亡率并改善其生活质量。尽管器官移植需求持续上升,但器官捐赠供应仍无法满足需求。器官短缺、高昂费用和漫长的等待名单引发了对可能不道德途径的渴望。这个被称为移植旅游的过程是指前往另一个国家购买器官用于移植。与国内肝移植相比,肝移植旅游与移植后并发症及更高的死亡率相关。在出国进行肝移植的患者中,存在移植前后感染筛查不当、机会性感染预防不足以及失访等问题。了解移植旅游的风险对于预防发病和死亡至关重要。