Resnicow K, Morley-Kotchen J, Wynder E
Division of Health Promotion Research, American Health Foundation, New York, New York 10017.
Pediatrics. 1989 Dec;84(6):969-76.
Medical and public health recommendations regarding detection and treatment of hyperlipidemia in children have generally been based on two principal epidemiologic studies: the Lipids Research Clinics Population Study (1972 to 1976) and the Bogalusa Heart Study (1973 to 1974). The present study was initiated to further describe the distribution of plasma cholesterol levels in a multiracial sample of American children. Between 1984 and 1988, the total cholesterol levels of 6585 children from 22 schools were measured as part of the Know Your Body School Health Program. For the entire population, ages 5 to 18 years, the mean total cholesterol concentration was 166.4 mg/dL. Total cholesterol was significantly greater in girls (168 mg/dL) than in boys (165 mg/dL), although sex differences were inconsistent across race/ethnicity. The mean value for blacks, 173 mg/dL, and Hispanics, 168 mg/dL, was higher than for Asians, 165 mg/dL, and whites, 163 mg/dL. Across race/ethnicity, values tended to peak between ages 8 and 10 years for girls and approximately 10 years of age for boys. These values are slightly higher than those reported in the Lipids Research Clinics and Bogalusa studies. Public health implications of these findings are discussed.
关于儿童高脂血症检测与治疗的医学及公共卫生建议，通常基于两项主要的流行病学研究：脂质研究临床人群研究（1972年至1976年）以及博加卢萨心脏研究（1973年至1974年）。本研究旨在进一步描述美国儿童多种族样本中血浆胆固醇水平的分布情况。在1984年至1988年期间，作为“了解你的身体”学校健康项目的一部分，对来自22所学校的6585名儿童的总胆固醇水平进行了测量。对于年龄在5至18岁的全体人群，平均总胆固醇浓度为166.4毫克/分升。女孩（168毫克/分升）的总胆固醇水平显著高于男孩（165毫克/分升），尽管性别差异在不同种族/族裔中并不一致。黑人的平均值为173毫克/分升，西班牙裔为168毫克/分升，高于亚洲人（165毫克/分升）和白人（163毫克/分升）。在不同种族/族裔中，女孩的数值往往在8至10岁达到峰值，男孩约在10岁达到峰值。这些数值略高于脂质研究临床及博加卢萨研究报告中的数值。本文讨论了这些研究结果对公共卫生的影响。
