Boumerfeg M, Aurousseau M H, Le Roux G, Lortholary P
Laboratoire Central d'Hématologie, Hôpital Jean Verdier, Bondy, France.
Nouv Rev Fr Hematol (1978). 1989;31(5):359-61.
Activated partial thromboplastin time is one of the most frequently used assay in haemostasis investigation, but sampling of venous blood is often difficult in newborns (as well as some adult patients). We analysed a method described by Zondag et al [9] performed on capillary blood samples. We studied normal adults and newborns, patients with liver diseases, and those receiving therapy with vitamin K antagonists and heparin. Capillary assay was correlated with venous blood in normal subjects, in patients with liver diseases and during therapy by vitamin K antagonists. However results both in newborns and adults during heparin therapy were not accurate.
活化部分凝血活酶时间是止血检查中最常用的检测方法之一,但在新生儿(以及一些成年患者)中采集静脉血往往很困难。我们分析了Zondag等人[9]描述的一种用于毛细血管血样的方法。我们研究了正常成年人和新生儿、肝病患者以及接受维生素K拮抗剂和肝素治疗的患者。在正常受试者、肝病患者以及维生素K拮抗剂治疗期间,毛细血管检测与静脉血检测结果相关。然而,在肝素治疗期间,新生儿和成年人的检测结果都不准确。