Yang Chun, Zhi Xiaoyan, Xu Hui
Research Institute of Pesticidal Design & Synthesis, College of Science, Northwest A&F University, Yangling 712100, Shaanxi Province, China.
Research Institute of Pesticidal Design & Synthesis, College of Science, Northwest A&F University, Yangling 712100, Shaanxi Province, China.
Bioorg Med Chem Lett. 2015;25(10):2217-9. doi: 10.1016/j.bmcl.2015.03.052. Epub 2015 Mar 25.
A series of novel benzoxazole compounds derived from a naturally occurring neolignan honokiol were prepared. Their insecticidal activity was tested against the pre-third-instar larvae of oriental armyworm (Mythimna separata Walker) in vivo. Most of the tested derivatives exhibited more potential insecticidal activity than their precursor honokiol at the concentration of 1mg/mL. Especially compound 6e, containing 4-acetyloxyphenyl groups at the C8 and C8' positions, displayed the most potent insecticidal activity with the final mortality rate of 62.1%.
制备了一系列源自天然新木脂素厚朴酚的新型苯并恶唑化合物。在体内对东方粘虫（Mythimna separata Walker）三龄前幼虫测试了它们的杀虫活性。在1mg/mL浓度下，大多数测试衍生物比其前体厚朴酚表现出更大的潜在杀虫活性。特别是在C8和C8'位含有4-乙酰氧基苯基的化合物6e，表现出最强的杀虫活性，最终死亡率为62.1%。
