Korzets Asher, Tsitman Inna, Lev Netta, Zingerman Boris, Herman Michal, Ben Dor Naomi, Gafter Uzi, Ori Yaacov
Department of Nephrology and Hypertension , Hasharon Hospital, Rabin Medical Center, Sackler School of Medicine , Tel Aviv University , Israel.
Department of Radiology , Hasharon Hospital, Rabin Medical Center, Sackler School of Medicine , Tel Aviv University , Israel.
Clin Kidney J. 2012 Aug;5(4):331-3. doi: 10.1093/ckj/sfs073. Epub 2012 Jul 6.
Lanthanum carbonate (LC) is used as a phosphate binder in dialysed patients. Abdominal pain and constipation are known side effects of its use. Furthermore, in radiological studies, LC tablets are seen as intense radio-opaque deposits within the entire gastrointestinal tract-findings which can lead to diagnostic misinterpretations. An elderly patient on peritoneal dialysis and taking LC presented with peritonitis, secondary to a perforated colonic diverticulum. The possible association between the use of LC, worsening constipation and complications arising from colonic diverticular disease, are discussed.
碳酸镧(LC)被用作透析患者的磷结合剂。腹痛和便秘是其已知的副作用。此外,在放射学研究中,LC片剂在整个胃肠道内表现为强烈的不透射线沉积物,这些发现可能导致诊断错误。一名接受腹膜透析并服用LC的老年患者出现了因结肠憩室穿孔继发的腹膜炎。本文讨论了使用LC、便秘加重与结肠憩室病引起的并发症之间可能存在的关联。