Ryu Samuel, Yoon Hannah, Stessin Alexander, Gutman Fred, Rosiello Arthur, Davis Raphael
Department of Radiation Oncology, Stony Brook University, Stony Brook, NY, USA. ; Department of Neurological Surgery, Stony Brook University, Stony Brook, NY, USA.
Department of Radiation Oncology, Stony Brook University, Stony Brook, NY, USA.
Radiat Oncol J. 2015 Mar;33(1):1-11. doi: 10.3857/roj.2015.33.1.1. Epub 2015 Mar 31.
With the progress of image-guided localization, body immobilization system, and computerized delivery of intensity-modulated radiation delivery, it became possible to perform spine radiosurgery. The next question is how to translate the high technology treatment to the clinical application. Clinical trials have been performed to demonstrate the feasibility of spine radiosurgery and efficacy of the treatment in the setting of spine metastasis, leading to the randomized trials by a cooperative group. Radiosurgery has also demonstrated its efficacy to decompress the spinal cord compression in selected group of patients. The experience indicates that spine radiosurgery has a potential to change the clinical practice in the management of spine metastasis and spinal cord compression.
随着图像引导定位、身体固定系统以及调强放射治疗的计算机化递送技术的进步,开展脊柱放射外科手术成为可能。接下来的问题是如何将这种高科技治疗方法转化为临床应用。已经开展了临床试验以证明脊柱放射外科手术在脊柱转移瘤治疗中的可行性和疗效,进而促成了一个协作组进行的随机试验。放射外科手术在特定患者群体中也已证明其在缓解脊髓压迫方面的疗效。这些经验表明,脊柱放射外科手术有可能改变脊柱转移瘤和脊髓压迫治疗的临床实践。