Robbins Jared, Wollner Ira, Ryu Samuel
Department of Radiation Oncology, Henry Ford Hospital, Detroit MI, USA.
Department of Hematology and Oncology, Henry Ford Hospital, Detroit MI, USA.
J Radiosurg SBRT. 2011;1(1):71-74.
Radiation recall dermatitis has been documented to occur in previously irradiated skin (within the radiation port) the administration of some chemotherapeutic agents. Clinically, it can occur weeks or months after radiation therapy, and resembles the appearance of acute radiation skin reaction. The patterns of the reaction correspond with radiation fields and skin doses. We report a case of recall dermatitis 8 weeks after of spine radiosurgery initiated by the use of a multi-targeted tyrosine kinase inhibitor, Sorafenib, used for treatment of hepatocellular carcinoma.
放射性回忆性皮炎已被证实可发生于先前接受过放疗的皮肤(放疗野内)在使用某些化疗药物之后。临床上,它可在放疗后数周或数月出现,外观类似于急性放射性皮肤反应。反应模式与放疗野及皮肤剂量相对应。我们报告一例在用于治疗肝细胞癌的多靶点酪氨酸激酶抑制剂索拉非尼引发脊柱放射外科手术后8周出现的回忆性皮炎病例。