Lopez Rodrigo, Hujoel Philippe, Belibasakis Georgios N
a Section of Periodontology; Faculty of Health Sciences; Aarhus University ; Aarhus , Denmark.
Virulence. 2015;6(3):249-57. doi: 10.1080/21505594.2015.1014266.
The current understanding on the role of microbiology on periodontitis causation is reviewed. An appraisal of the literature reveals several issues that have limited the attempts to investigate candidate periodontal pathogens as causes of periodontitis and confirms that only limited epidemiological evidence is available. Several aspects of the contemporary understanding on causal inference are discussed with examples for periodontitis.
本文综述了目前对微生物学在牙周炎病因中作用的理解。对文献的评估揭示了几个问题，这些问题限制了将牙周炎候选病原体作为病因进行研究的尝试，并证实仅有有限的流行病学证据。文中结合牙周炎的实例讨论了当代因果推断理解的几个方面。
