Kostromina V P, Kogosova L S, Zagoruĭko N L, Pekurovskiĭ E M
Probl Tuberk. 1989(9):25-8.
Seventy-eight tuberculin-positive schoolchildren at the age of 7 to 15 years from tuberculosis foci living in special institutions of the sanatorium type were subjected to immunological examination. The control group included 22 noninfected children of the same age. Persons with lower counts of T-lymphocytes and their decreased functional activity, unbalance in their subpopulation composition and positive immunospecific responses to tuberculin predominated among the schoolchildren subjected to the examination. The state of the B-lymphocyte system changed insignificantly. It was concluded that persons with markedly suppressed cellular immunity be treated with immunomodulating agents during the chemoprophylaxis course.
对来自疗养院类型特殊机构中结核病疫源地的78名7至15岁结核菌素呈阳性的学童进行了免疫学检查。对照组包括22名同龄未受感染的儿童。接受检查的学童中,T淋巴细胞计数较低、功能活性降低、亚群组成失衡以及对结核菌素呈阳性免疫特异性反应的人占多数。B淋巴细胞系统的状态变化不明显。得出的结论是,在化学预防过程中,应对细胞免疫明显受到抑制的人使用免疫调节剂进行治疗。