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一名患有神经性厌食症的年轻女性出现骨软化症、严重胸廓畸形和呼吸衰竭。

Osteomalacia, severe thoracic deformities and respiratory failure in a young woman with anorexia nervosa.

作者信息

Watanabe Daisuke, Hotta Mari, Ichihara Atsuhiro

机构信息

Department of Endocrinology and Hypertension, Tokyo Women's Medical University, Japan.

出版信息

Intern Med. 2015;54(8):929-34. doi: 10.2169/internalmedicine.54.3673. Epub 2015 Apr 15.

Abstract

The recent trends in avoiding sunbathing and eating fewer fish products have resulted in a high prevalence of vitamin D deficiency in the general Japanese population. We herein report the case of a young woman with enduring anorexia nervosa (AN) who suffered from osteomalacia, thoracic deformities and respiratory failure. Her vitamin D deficiency had been overlooked for years. Although the serum 25-hyroxyvitamin D [25(OH)D] level is a marker of vitamin D stores, it is not routinely examined because the cost is not covered by the national health insurance program. However, measuring the serum 25(OH)D levels in AN patients with hypocalcemia is recommended to prevent osteomalacia and osteoporosis.

摘要

近期避免日光浴和减少鱼类产品摄入的趋势导致日本普通人群中维生素D缺乏症的高患病率。我们在此报告一例患有持续性神经性厌食症(AN)的年轻女性病例,她患有骨软化症、胸廓畸形和呼吸衰竭。她的维生素D缺乏多年来一直被忽视。尽管血清25-羟维生素D [25(OH)D] 水平是维生素D储备的标志物,但由于国家医疗保险计划不涵盖此项费用,所以通常不进行检测。然而,建议对患有低钙血症的AN患者测量血清25(OH)D水平,以预防骨软化症和骨质疏松症。

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