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成人膀胱外翻原发性鳞状细胞癌

Primary squamous cell carcinoma of bladder exstrophy in an adult.

作者信息

Bhat Suresh, Sathyanarayanaprasad Manjunatha, Paul Fredrick

机构信息

Department of Urology, Government Medical College, Kottayam, Kerala, India.

出版信息

Indian J Urol. 2015 Apr-Jun;31(2):142-3. doi: 10.4103/0970-1591.152920.

DOI:10.4103/0970-1591.152920
PMID:25878418
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4397553/
Abstract

Exstrophy of the urinary bladder is a rare congential anomaly. The most common malignancy is an adenocarcinoma in these patients. Squamous cell carcinoma (SCC) occurring in these patients is uncommon and usually has a bad prognosis. The management of these patients is challenging and may require extensive reconstructive procedures. We report a case of SCC in a corrected bladder exstrophy patient who presented with an ulcerated mass in the lower abdomen extending to the base of the penis. Six months after extensive radical ablative surgery with reconstruction of the abdominal wall, the patient remained free of recurrence.

摘要

膀胱外翻是一种罕见的先天性畸形。这些患者中最常见的恶性肿瘤是腺癌。这些患者发生的鳞状细胞癌（SCC）并不常见，且通常预后不良。这些患者的治疗具有挑战性，可能需要广泛的重建手术。我们报告一例膀胱外翻矫正患者发生SCC的病例，该患者下腹部出现溃疡性肿物，肿物延伸至阴茎根部。在进行广泛根治性切除手术并重建腹壁6个月后，患者未出现复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c26a/4397553/67b3e079b5e1/IJU-31-142-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c26a/4397553/a6c0b74da6e4/IJU-31-142-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c26a/4397553/e6a1d09eb0c9/IJU-31-142-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c26a/4397553/67b3e079b5e1/IJU-31-142-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c26a/4397553/a6c0b74da6e4/IJU-31-142-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c26a/4397553/e6a1d09eb0c9/IJU-31-142-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c26a/4397553/67b3e079b5e1/IJU-31-142-g003.jpg

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本文引用的文献

1
Outcome and patterns of recurrence of nonbilharzial pure squamous cell carcinoma of the bladder: a contemporary review of The University of Texas M D Anderson Cancer Center experience.膀胱非血吸虫性纯鳞状细胞癌的治疗结果及复发模式：德克萨斯大学MD安德森癌症中心经验的当代综述
Cancer. 2007 Aug 15;110(4):764-9. doi: 10.1002/cncr.22853.
2
Long-term results of primary adenocarcinoma of the urinary bladder: a report on 192 patients.膀胱原发性腺癌的长期结果：192例患者的报告。
Urol Oncol. 2006 Jan-Feb;24(1):13-20. doi: 10.1016/j.urolonc.2005.05.027.
3
Neoplasia in adult exstrophy patients.
农药和膀胱癌：导致抗癌药物化疗耐药性的机制和新的化疗增敏策略。
Int J Mol Sci. 2023 Jul 13;24(14):11395. doi: 10.3390/ijms241411395.
4
Management of cavernous abdominal wall defects post radical cystectomy in adult exstrophy complex.成人泄殖腔外翻综合征根治性膀胱切除术后海绵状腹壁缺损的处理
BMJ Case Rep. 2019 Jan 14;12(1):bcr-2018-226076. doi: 10.1136/bcr-2018-226076.
成人膀胱外翻患者的肿瘤形成
BJU Int. 2001 Oct;88(6):647-8. doi: 10.1046/j.1464-4096.2001.2429.x-i7.