Bhardwaj Ekta K, Trüeb Ralph Michel
Renovia Medical Aesthetics and Hair Center, Manchester, England, UK.
Center for Dermatology and Hair Diseases, Zurich-Wallisellen, Switzerland.
Int J Trichology. 2015 Jan-Mar;7(1):26-8. doi: 10.4103/0974-7753.153454.
A case of acute diffuse and total alopecia of the female scalp associated with Borrelia-infection (acrodermatitis chronica atrophicans) is presented. Today, acute diffuse and total alopecia of the female scalp is recognized as a distinct variant of alopecia areata (AA) predominantly observed in women. Cases of AA have formerly been reported in association with infections. AA is understood to represent an organ-specific autoimmune disease of the hair follicle. It is conceivable that the antigenic stimulus provided by the infection may act as a trigger for alopecia. Vice versa, alopecia may act as a marker for detection of undiagnosed infection. Treatment of the patient with intravenous ceftriaxone led to the resolution of cutaneous borreliosis, and in addition to topical clobetasol foam to complete recovery of hair.
本文报告一例与伯氏疏螺旋体感染（慢性萎缩性肢端皮炎）相关的女性头皮急性弥漫性全秃病例。如今，女性头皮急性弥漫性全秃被认为是斑秃（AA）的一种独特变体，主要见于女性。既往曾有AA病例与感染相关的报道。AA被认为是一种毛囊特异性自身免疫性疾病。可以想象，感染提供的抗原刺激可能触发脱发。反之，脱发可能作为未确诊感染的检测标志物。对该患者静脉注射头孢曲松治疗后，皮肤型莱姆病得到缓解，除外用氯倍他索泡沫外，头发也完全恢复。
