Kadir Mohammad Fahim, Karmoker James Regun, Alam Md Rashedul, Jahan Syeda Rawnak, Mahbub Sami, Mia M M K
Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh ; Department of Pharmacy, University of Asia Pacific, Dhaka 1209, Bangladesh.
Department of Pharmacy, University of Asia Pacific, Dhaka 1209, Bangladesh.
Evid Based Complement Alternat Med. 2015;2015:871675. doi: 10.1155/2015/871675. Epub 2015 Mar 23.
Snakebites are common in tropical countries like Bangladesh where most snakebite victims dwell in rural areas. Among the management options after snakebite in Bangladesh, snake charmers (Ozha in Bengali language) are the first contact following a snakebite for more than 80% of the victims and they are treated mostly with the help of some medicinal plants. Our aim of the study is to compile plants used for the treatment of snakebite occurrence in Bangladesh. The field survey was carried out in a period of almost 3 years. Fieldwork was undertaken in Chittagong Hill Tracts, Bangladesh, including Chittagong, Rangamati, Bandarban, and Khagrachari. Open-ended and semistructured questionnaire was used to interview a total of 110 people including traditional healers and local people. A total of 116 plant species of 48 families were listed. Leaves were the most cited plant part used against snake venom. Most of the reported species were herb in nature and paste mostly used externally is the mode of preparation. The survey represents the preliminary information of certain medicinal plants having neutralizing effects against snake venoms, though further phytochemical investigation, validation, and clinical trials should be conducted before using these plants as an alternative to popular antivenom.
在孟加拉国等热带国家,蛇咬伤很常见,那里大多数蛇咬伤受害者居住在农村地区。在孟加拉国,蛇咬伤后的处理方式中,超过80%的受害者在被蛇咬后首先会联系耍蛇人(孟加拉语称“奥扎”),他们大多借助一些药用植物进行治疗。我们这项研究的目的是汇编孟加拉国用于治疗蛇咬伤的植物。实地调查进行了近3年。在孟加拉国的吉大港山区开展了实地工作,包括吉大港、朗加马蒂、班达班和卡格拉乔里。使用开放式和半结构化问卷对包括传统治疗师和当地人在内的总共110人进行了访谈。共列出了48科的116种植物。叶子是最常被提及的用于对抗蛇毒的植物部位。报告的大多数物种本质上是草本植物,最常用的外用剂型是糊剂。该调查提供了某些对蛇毒有中和作用的药用植物的初步信息,不过在将这些植物用作常用抗蛇毒血清的替代品之前,应进行进一步的植物化学研究、验证和临床试验。