Hasan Md Nazmul, Azam Nur Kabidul, Ahmed Md Nasir, Hirashima Akinori
Laboratory of Pesticide Chemistry, Division of Molecular Biosciences, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka 812-8581, Japan; Department of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jessore University of Science & Technology, Jessore 7408, Bangladesh.
Tech B Herbal Solution, Bheramara Kushtia, Bangladesh.
J Tradit Complement Med. 2015 Apr 21;6(4):337-342. doi: 10.1016/j.jtcme.2015.03.007. eCollection 2016 Oct.
Snakebite is the single most important toxin-related injury, causing substantial mortality in many parts of the Africa, Asia and the Americas. Incidence of snakebite is usually recorded in young people engaged in active physical work in rural areas. The various plant parts used to treat snakebite included whole plant, leaves, barks, roots and seeds. Most bites in Bangladesh are recorded between May and October with highest number in June. Lower and upper limbs are most common sites of snakebite, but it may happen in other sites as well. Snake venom ( shé dú) has been the cause of innumerable deaths worldwide. However, antiserum does not provide enough protection against venom induced hemorrhage, necrosis, nephrotoxicity and hypersensitivity reactions. Informed consent was obtained from the practitioners prior to interviews. After the survey, it is concluded that the medicinal plants used by tribal medicinal practitioners in Bangladesh for treatment against snakebite are L. ( tǔ niú xī), L. ( yě xiàng cài), Willd ( zǒng xù tiān dōng) and Gaertn ( yóu gān), while the non-tribal communities used 35 plant species among them, most of the plants reported as new species used against snakebite in the belonging family. The plants present a considerable potential for discovery of novel compounds with fewer side effects for treatment of antisnake venom and can, at least in Bangladesh, become a source of affordable and more easily available drugs.
蛇咬伤是与毒素相关的最为重要的单一损伤,在非洲、亚洲和美洲的许多地区造成了大量死亡。蛇咬伤的发病率通常记录在农村地区从事体力劳动的年轻人中。用于治疗蛇咬伤的各种植物部位包括整株植物、叶子、树皮、根和种子。孟加拉国的大多数咬伤记录在5月至10月之间,6月的数量最多。下肢和上肢是蛇咬伤最常见的部位,但其他部位也可能发生。蛇毒在全球范围内已导致无数人死亡。然而,抗蛇毒血清并不能为毒液引起的出血、坏死、肾毒性和过敏反应提供足够的保护。在采访之前,已从从业者那里获得知情同意。调查结束后得出结论,孟加拉国部落行医者用于治疗蛇咬伤的药用植物有土牛膝、野香菜、总序天门冬和油柑,而非部落社区使用了其中的35种植物,其中大多数植物被报告为所属科中用于治疗蛇咬伤的新物种。这些植物具有发现副作用较少的新型化合物以治疗抗蛇毒血清的巨大潜力,并且至少在孟加拉国,可以成为负担得起且更容易获得的药物来源。