Chakraborty Partha Pratim, Ray Sayantan, Selvan Chitra, Bhattacharjee Rana, Mandal Sanjay Kumar
Partha Pratim Chakraborty, Sayantan Ray, Chitra Selvan, Rana Bhattacharjee, Department of Endocrinology, IPGMER and SSKM Hospital, Kolkata 700020, West Bengal, India.
World J Clin Cases. 2015 Apr 16;3(4):385-8. doi: 10.12998/wjcc.v3.i4.385.
Authors describe a 53-year-old woman who presented to their diabetes clinic with a three week history of multiple painful and swollen joints. She had been diagnosed with type 2 diabetes 5 years back. On examination, both knee joints and left ankle were swollen. A soft tissue swelling appeared over the medial end of the left clavicle few days later. Rheumatoid arthritis, collagen vascular diseases and other common causes of polyarthritis were ruled out by appropriate investigations. Non steroidal anti-inflammatory drugs failed to give satisfactory pain relief and the arthritis persisted. Conventional cultures of synovial fluid samples including cultures for tuberculosis were negative. Computed tomography showed a space occupying lesion involving the left sternoclavicular joint. Fine needle aspiration from the lesion was performed and acid-fast bacilli were demonstrated in the smear using Ziehl-Neelsen stain. The explanation of her arthritis was therefore tuberculous arthritis in left sternoclavicular joint and reactive arthritis in the rest of the joints. A diagnosis of Poncet's disease was considered in her case. We treated her with standard anti-tuberculosis drugs and the arthritis resolved within a few days. She remained symptom-free at her 2 years' follow-up.
作者描述了一名53岁女性,她因多个关节疼痛和肿胀三周前往他们的糖尿病诊所就诊。她在5年前被诊断为2型糖尿病。检查时,双膝关节和左踝关节肿胀。几天后,左锁骨内侧端出现软组织肿胀。通过适当检查排除了类风湿性关节炎、胶原血管疾病和多关节炎的其他常见病因。非甾体抗炎药未能有效缓解疼痛,关节炎持续存在。滑膜液样本的常规培养,包括结核培养,均为阴性。计算机断层扫描显示左胸锁关节有占位性病变。对病变进行了细针穿刺抽吸,并用齐-尼氏染色法在涂片中发现了抗酸杆菌。因此,她关节炎的病因是左胸锁关节结核性关节炎,其余关节为反应性关节炎。考虑她的病例为蓬塞氏病。我们用标准抗结核药物治疗她,关节炎在几天内消退。在两年的随访中,她一直无症状。