Omonge Enoch, Otieno Fredrick, Kubo Mary, Shiruli Betty
University of Nairobi, Nairobi, Kenya.
BMC Res Notes. 2017 Jun 12;10(1):203. doi: 10.1186/s13104-017-2525-9.
Poncet's disease is a rare reactive polyarthritis associated with active tuberculosis and no evidence of Mycobacterium tuberculosis in the affected joint.
We report a case of a 35 year old Human Immunodeficiency Virus positive Kenyan male of Kikuyu ethnicity from Kiambu County who presented to hospital with a 6 day history of bilateral knee pain and swelling, bilateral ankle pain with right ankle swelling. The patient reported 6 months history of cough and weight loss. Chest radiograph had features consistent with pulmonary tuberculosis and sputum smear was positive for acid fast bacilli. Analysis of fluid from knee effusion showed no evidence of tuberculosis. Resolution of joint swelling was seen after 3 weeks of tuberculosis chemotherapy suggesting that this was reactive arthritis following pulmonary tuberculosis in a patient infected with human immunodeficiency virus.
This case represents a rare manifestation of tuberculosis presenting as a reactive arthritis. There are very few cases of Poncet's disease reported in literature and the diagnosis of Poncet's disease in Human Immunodeficiency Virus/tuberculosis coinfected patient is extremely uncommon. This case report has been presented to raise awareness of this unusual tuberculosis complication and review its diagnosis and treatment.
蓬塞病是一种罕见的反应性多关节炎,与活动性肺结核相关,且受累关节无结核分枝杆菌证据。
我们报告一例35岁的肯尼亚基库尤族男性,来自基安布县,人类免疫缺陷病毒阳性。该患者因双侧膝关节疼痛肿胀、双侧踝关节疼痛伴右踝关节肿胀6天入院。患者自述有6个月咳嗽和体重减轻病史。胸部X光片表现符合肺结核,痰涂片抗酸杆菌阳性。膝关节积液分析未发现结核证据。抗结核化疗3周后关节肿胀消退,提示这是一名感染人类免疫缺陷病毒患者发生的肺结核后反应性关节炎。
该病例代表了以反应性关节炎形式出现的罕见肺结核表现。文献中报道的蓬塞病病例极少,在人类免疫缺陷病毒/肺结核合并感染患者中诊断蓬塞病极为罕见。本病例报告旨在提高对这种不寻常肺结核并发症的认识,并对其诊断和治疗进行回顾。