Yuan Zhang, Quan Jiang, Yunxiao Zhang, Jian Chen, Zhu He
Department of Ultrasound, Shanghai Pudong New Area People's Hospital, Pudong, Shanghai, China.
J Cancer Res Ther. 2015 Jan-Mar;11(1):41-5. doi: 10.4103/0973-1482.147382.
The aim was to study the patterns of solitary thyroid nodule with real-time contrast-enhanced ultrasound (CEUS) and assess its value in differentiating between malignant and benign thyroid nodules.
Seventy-eight patients with solitary thyroid nodule (37 malignant, 41 benign) underwent real-time CEUS. The patterns of their enhancement were assessed from six aspects: Degree of enhancement, process of enhancement, homogeneity of enhancement, completeness of enhancement, boundary of the enhanced lesions, and shape of the enhanced lesions.
Contrast-enhanced patterns were significantly different between benign and malignant thyroid nodules (P < 0.05), except for process of enhancement. The shape of most malignant lesions was irregular (94.59%), the boundary was unclear (86.49%) and had no significantly enhanced (78.38%). Most malignant lesions became inhomogeneously (78.38%) and incompletely enhanced (70.27%).
The patterns of real-time CEUS are significantly different between benign and malignant thyroid nodules, and have important clinical value.
研究实时超声造影（CEUS）下甲状腺单发结节的特征，并评估其在鉴别甲状腺良恶性结节中的价值。
78例甲状腺单发结节患者（37例为恶性，41例为良性）接受了实时CEUS检查。从增强程度、增强过程、增强均匀性、增强完整性、增强病灶边界及增强病灶形态六个方面评估其增强特征。
除增强过程外，甲状腺良恶性结节的超声造影特征差异有统计学意义（P < 0.05）。多数恶性病灶形态不规则（94.59%），边界不清（86.49%），无明显增强（78.38%）。多数恶性病灶呈不均匀增强（78.38%）和不完整增强（70.27%）。
甲状腺良恶性结节的实时CEUS特征差异有统计学意义，具有重要的临床价值。
