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一例罕见的外阴神经鞘瘤病例。

An unusual case of vulvar schwannoma.

作者信息

Park Sung Taek, Kim Han Myun, Shin Mi Kyung, Kim Ji Won

机构信息

Department of Obstetrics and Gynecology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, 150-950, Korea.

Department of Radiology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, 150-950, Korea.

出版信息

World J Surg Oncol. 2015 Apr 8;13:139. doi: 10.1186/s12957-015-0556-z.

DOI:10.1186/s12957-015-0556-z
PMID:25879436
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4391467/
Abstract

Schwannoma is a benign, solitary, slow-growing neoplasm of the peripheral nerve sheath. These tumors are rarely found in the external genital system, and only a few cases of vulvar schwannoma have been reported. Herein, we report a case of a vulvar schwannoma. A 37-year-old woman presented with a 3-cm-sized painless mass of the vulva which had been present for 3 years. Magnetic resonance imaging (MRI) of the pelvis showed an isolated finding of a 4.6-cm-sized round mass with a well-defined margin in the midline vulvar area. Simple excision of the tumor was undertaken, and histological examination with immunohistochemical testing demonstrated a vulvar schwannoma. Although benign schwannoma only rarely occurs in the vulva and other external areas of female genitalias, we suggest that it should be considered a differential diagnosis for patients that present a vulvar enlargement or mass. Simple surgical resection and follow-up is the most convenient treatment.

摘要

神经鞘瘤是一种起源于周围神经鞘的良性、孤立性、生长缓慢的肿瘤。这些肿瘤在女性外生殖器系统中很少见,仅有少数外阴神经鞘瘤的病例报道。在此,我们报告一例外阴神经鞘瘤。一名37岁女性,外阴出现一个3厘米大小的无痛性肿块,已存在3年。骨盆磁共振成像(MRI)显示,在外阴中线区域有一个孤立的4.6厘米大小的圆形肿块,边界清晰。对肿瘤进行了单纯切除,组织学检查及免疫组化检测证实为外阴神经鞘瘤。尽管良性神经鞘瘤很少发生于外阴及女性生殖器的其他外部区域,但我们建议,对于出现外阴肿大或肿块的患者,应将其纳入鉴别诊断范围。单纯手术切除及随访是最简便的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/38eea3343303/12957_2015_556_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/28230d9b4db8/12957_2015_556_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/87fecb6ec043/12957_2015_556_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/1c543eb64b4d/12957_2015_556_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/41fa9d8694cd/12957_2015_556_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/38eea3343303/12957_2015_556_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/28230d9b4db8/12957_2015_556_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/87fecb6ec043/12957_2015_556_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/1c543eb64b4d/12957_2015_556_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/41fa9d8694cd/12957_2015_556_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8af/4391467/38eea3343303/12957_2015_556_Fig5_HTML.jpg

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本文引用的文献

1
Plexiform schwannoma of the clitoris in a young girl: a case report.
J Reprod Med. 2013 Jul-Aug;58(7-8):365-8.
2
Giant vulvar schwannoma: a case report.巨大型外阴神经鞘瘤:一例报告
Acta Med Iran. 2013 Jul 13;51(6):427-9.
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Perineal schwannoma.会阴神经鞘瘤
Can J Surg. 2009 Feb;52(1):E8-9.
Indian J Surg Oncol. 2017 Sep;8(3):414-416. doi: 10.1007/s13193-017-0638-1. Epub 2017 Mar 9.
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A Case of Vulvar Schwannoma Mimicking Epidermoid Cyst.1例酷似表皮样囊肿的外阴神经鞘瘤
Case Rep Dermatol. 2018 Feb 15;10(1):41-45. doi: 10.1159/000487125. eCollection 2018 Jan-Apr.
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Clinician's Update on the Benign, Premalignant, and Malignant Skin Tumours of the Vulva: The Dermatologist's View.临床医生对外阴良性、癌前和恶性皮肤肿瘤的最新认识:皮肤科医生的观点
Int Sch Res Notices. 2017 Jul 25;2017:2414569. doi: 10.1155/2017/2414569. eCollection 2017.
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Ancient schwannoma of the vulva.外阴陈旧性神经鞘瘤。
Obstet Gynecol. 2009 Feb;113(2 Pt 2):510-512. doi: 10.1097/AOG.0b013e318188042f.
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Schwannoma of the clitoris.
Acta Obstet Gynecol Scand. 2002 May;81(5):471-2. doi: 10.1034/j.1600-0412.2002.810517.x.
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Case report: plexiform schwannoma of the vulva.
Pathology. 2001 Nov;33(4):526-31. doi: 10.1080/00313020120083313.
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A case of vulvar schwannoma.一例外阴神经鞘瘤。
J Obstet Gynaecol Res. 1996 Feb;22(1):31-4. doi: 10.1111/j.1447-0756.1996.tb00932.x.
10
Malignant schwannoma of the vulva. A case report.
J Reprod Med. 1988 Dec;33(12):969-72.