Khanam Masuma Akter, Lindeboom Wietze, Razzaque Abdur, Niessen Louis, Milton Abul Hasnat
Centre for Control of Chronic Diseases in Bangladesh, icddr,b, Dhaka, 1212, Bangladesh.
Centre for Clinical Epidemiology and Biostatistics (CCEB), School of Medicine and Public Health, the University of Newcastle, Callaghan, NSW, 2308, Australia.
BMC Public Health. 2015 Feb 28;15:203. doi: 10.1186/s12889-015-1520-0.
The people of low and middle income countries bear about 80% of the global burden of diseases that are attributable to high blood pressure. Hypertensive people contribute half of this burden; the rest is among the people with lesser degrees of high blood pressure. Prehypertension elevates the risk of CVD, and that of end-stage renal disease. Bangladesh is a developing country, with more than 75% of the population live in rural area. This study aims to determine the prevalence and predictors of pre-hypertension and hypertension among the adults in rural Bangladesh.
A cross-sectional study of major non-communicable disease risk factors (tobacco and alcohol use, fruit and vegetable intake, physical activity) was conducted in rural surveillance sites of Bangladesh. In addition to the self-reported information on risk factors, height and weight, and blood pressure were measured during household visits using standard protocols of the WHO STEPwise approach to Surveillance. The study population included 6,094 men and women aged 25 years and above. Adjusted and unadjusted logistic regression analyses were performed to evaluate the association of prehypertension and hypertension with various factors.
The prevalence of pre-hypertension and hypertension was 31.9% and 16.0%, respectively. The men had a higher prevalence (33.6%) of pre-hypertension compared to the women (30.3%). Multivariate analysis showed that increasing age [OR 2.30 (1.84-2.87)] and higher BMI [OR 4.67 (3.35-6.51) were positively associated with pre-hypertension. For hypertension, multivariate analysis showed that increasing age [OR 4.48 (3.38-5.94)] and higher BMI (specially the overweight category) was positively associated. Significant linear relationships of prehypertension were found with age [P for trend < 0.0001] and BMI [P for trend < 0.0001]. Linear regression for hypertension shows significant association with age [P for trend < 0.0001] but not with BMI [P for trend 0.3783].
Approximately one third and one-sixth of the adult population of rural Bangladesh are affected with pre-hypertension and hypertension, respectively. This poses a great challenge ahead, as most of the people with pre-hypertension will progress towards hypertension until otherwise undergo in any pharmacological or lifestyle intervention.
低收入和中等收入国家的人群承担了约80%的全球高血压所致疾病负担。高血压患者承担了其中一半的负担;其余负担由血压升高程度较轻的人群承担。高血压前期会增加心血管疾病(CVD)和终末期肾病的风险。孟加拉国是一个发展中国家,超过75%的人口生活在农村地区。本研究旨在确定孟加拉国农村成年人中高血压前期和高血压的患病率及预测因素。
在孟加拉国农村监测点开展了一项关于主要非传染性疾病风险因素(烟草和酒精使用、水果和蔬菜摄入量、身体活动)的横断面研究。除了关于风险因素的自我报告信息外,在家庭访视期间使用世界卫生组织逐步监测方法的标准规程测量身高、体重和血压。研究人群包括6094名年龄在25岁及以上的男性和女性。进行了调整和未调整的逻辑回归分析,以评估高血压前期和高血压与各种因素的关联。
高血压前期和高血压的患病率分别为31.9%和16.0%。男性高血压前期患病率(33.6%)高于女性(30.3%)。多变量分析显示,年龄增加[比值比(OR)2.30(1.84 - 2.87)]和较高的体重指数(BMI)[OR 4.67(3.35 - 6.51)]与高血压前期呈正相关。对于高血压,多变量分析显示,年龄增加[OR 4.48(3.38 - 5.94)]和较高的BMI(特别是超重类别)呈正相关。发现高血压前期与年龄[趋势P值<0.0001]和BMI[趋势P值<0.0001]存在显著的线性关系。高血压的线性回归显示与年龄存在显著关联[趋势P值<0.0001],但与BMI无关联[趋势P值0.3783]。
孟加拉国农村约三分之一和六分之一的成年人口分别患有高血压前期和高血压。这带来了巨大挑战,因为大多数高血压前期患者在未接受任何药物或生活方式干预的情况下将发展为高血压。