基于 SERS 活性的 Au@Ag 纳米棒二聚体用于超高灵敏多巴胺检测。
SERS-active Au@Ag nanorod dimers for ultrasensitive dopamine detection.
机构信息
State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, JiangSu 214122, PR China.
Cereals & Oils Nutrition Research Group, Academy of Science & Technology of State Administration of Grain, Beijing 100037, PR China.
出版信息
Biosens Bioelectron. 2015 Sep 15;71:7-12. doi: 10.1016/j.bios.2015.04.013. Epub 2015 Apr 7.
Dopamine (DA) is a neurotransmitter which plays a key role in the life science. Self-assembled Au@Ag nanorod dimers based on aptamers were developed for ultrasensitive dopamine detection. The electronic field was significantly enhanced by the addition of silver shell coating on the surface of Au NR dimer. The results displayed that Au@Ag NR dimers were ideal building blocks for constructing the SERS substrates with prominent Raman enhancement effects. It was found that with using this Surface-enhanced Raman scattering (SERS)-encoded this sensing system, a limit of detection of 0.006 pM and a wide linear range of 0.01-10 pM for dopamine detection were obtained. Our work open up a new avenue for the diagnosis and drug-discovery programs.
多巴胺（DA）是一种神经递质，在生命科学中起着关键作用。基于适体的自组装 Au@Ag 纳米棒二聚体被开发用于超灵敏多巴胺检测。通过在 Au NR 二聚体表面添加银壳涂层，显著增强了电子场。结果表明，Au@Ag NR 二聚体是构建具有显著拉曼增强效应的 SERS 基底的理想构建块。研究发现，使用这种表面增强拉曼散射（SERS）编码传感系统，检测多巴胺的检测限达到 0.006 pM，线性范围为 0.01-10 pM。我们的工作为诊断和药物发现计划开辟了新的途径。
Zotero 插件