Coetzee A M, Becker P J
Institute for Biostatistics (Transvaal Branch), South African Medical Research Council, Johannesburg.
S Afr Med J. 1989 Nov 18;76(10):550-3.
Regression equations for forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) for 518 black factory workers on the Transvaal highveld were calculated from data obtained during routine lung function testing at an asbestos-cement factory. Only those subjects with clinically and radiologically normal lungs were accepted for the study. The lung capacities of the 60% who were light smokers were not significantly affected. Years of dust exposure were included as a separate independent variable and its contributory effect, after age had been allowed for, was insignificant. The final combined regression equations are considered to be representative of healthy black men on the Transvaal highveld. The values of FVC calculated from these equations were compared with values derived by other authors and, in view of the differences found, it was concluded that predicted values for black workers derived from regression equations for white subjects should not be used for industrial screening purposes. Group-specific equations should be followed when using lung function testing for definitive clinical diagnosis or academic research. The equations suggested for black South African men are FVC = 0.055 (height in cm) - 0.016 (age in years) - 4.502 and FEV1 = 0.043 (height) - 00023 (age) - 3.006.
根据在一家石棉水泥厂进行常规肺功能测试所获得的数据，计算了德兰士瓦高地518名黑人工厂工人的用力肺活量（FVC）和一秒用力呼气量（FEV1）的回归方程。该研究仅纳入临床和放射学检查肺部正常的受试者。60%轻度吸烟者的肺容量未受到显著影响。将接触粉尘的年限作为一个单独的自变量纳入，在考虑年龄因素后，其影响不显著。最终的综合回归方程被认为代表了德兰士瓦高地上健康的黑人男性。将根据这些方程计算出的FVC值与其他作者得出的值进行了比较，鉴于发现的差异，得出结论：不应将从白人受试者回归方程得出的黑人工人预测值用于工业筛查目的。在进行明确的临床诊断或学术研究而使用肺功能测试时，应遵循特定群体的方程。为南非黑人男性建议的方程为：FVC = 0.055（身高，单位：厘米） - 0.016（年龄，单位：岁） - 4.502，FEV1 = 0.043（身高） - 0.0023（年龄） - 3.006。
