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[治疗性血浆置换中血浆替代的问题(血浆替代介质的疗效评估及获取方法)]

[The problems of plasma substitution in performing therapeutic plasmapheresis (an evaluation of the efficacy of plasma substitute media and the methods for obtaining them)].

作者信息

Ryzhko V V, Gorodetskiĭ V M, Aleksanian M Zh, Margulis E Ia

出版信息

Ter Arkh. 1989;61(7):60-5.

PMID:2588145
Abstract

The analysis of 3700 plasmaphereses (AP) performed in 692 patients permitted the authors to develop the basic principles and policy of plasma substitution for various groups of patients. The use of protein preparations and fresh frozen plasma is believed essential in intensive plasmapheresis in patients with immunomediated disorders and DIC syndrome, respectively. Potentialities of selective therapeutic PA are discussed. PA criteria should be based on the patient's state, therapeutic aims, circulation parameters, laboratory data.

摘要

对692例患者进行的3700次血浆置换(AP)分析,使作者得以制定针对不同患者群体的血浆置换基本原则和策略。蛋白质制剂和新鲜冷冻血浆分别被认为是免疫介导疾病患者和弥散性血管内凝血(DIC)综合征患者进行强化血浆置换时必不可少的。文中讨论了选择性治疗性血浆置换(PA)的潜力。血浆置换标准应基于患者状态、治疗目的、循环参数及实验室数据。

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