Batra H S, Kumar Ashwini, Saha T K, Misra Pratibha, Ambade Vivek
Dept of Biochemistry, Armed Forces Medical College, Pune, 411040 Maharashtra India.
Indian J Clin Biochem. 2015 Apr;30(2):230-3. doi: 10.1007/s12291-013-0416-y. Epub 2014 Jan 24.
To establish utility of single enzymatic marker for the diagnosis of acute pancreatitis. This is a cohort study. Tertiary care centre proven cases of acute pancreatitis (n = 50) admitted in surgery ward between December 2011 and May 2013 were included in the study. Serum amylase and lipase were performed along with many analytes. All relevant data including serum lab values and imaging were collected. All 50 patients included in the study had raised serum lipase, 42 patients had both amylase and lipase raised, 8 patients had amylase normal but lipase raised. In smaller hospitals where limited lab and radiological facilities are available, estimation of serum lipase will be a better choice over serum amylase in diagnosis of acute pancreatitis.
建立单一酶标志物用于诊断急性胰腺炎的实用性。这是一项队列研究。纳入了2011年12月至2013年5月在外科病房收治的三级医疗中心确诊的急性胰腺炎病例(n = 50)。同时检测了血清淀粉酶和脂肪酶以及许多其他分析物。收集了所有相关数据,包括血清实验室值和影像学资料。研究纳入的50例患者血清脂肪酶均升高,42例患者淀粉酶和脂肪酶均升高,8例患者淀粉酶正常但脂肪酶升高。在实验室和放射学设施有限的小型医院,在诊断急性胰腺炎时,检测血清脂肪酶比检测血清淀粉酶是更好的选择。