Oh Hyung Sug, Kim Tae Wan, Park Kwan Ho
Department of Neurosurgery, VHS Medical Center, Seoul, Korea.
Korean J Spine. 2015 Mar;12(1):15-8. doi: 10.14245/kjs.2015.12.1.15. Epub 2015 Mar 31.
A teratoma is a neoplasm that contains tissues originating from three germ cell layers at ectopic sites. The embryology of teratomas remains unclear. Teratomas are usually composed of cystic and solid components, and they are usually associated with syringomyelia. Cystic lesions of teratomas may rupture in a spontaneous, iatrogenic, or traumatic manner. Lipid droplets in the ventricles and subarachnoid space are rare. We managed a case of a spinal teratoma in the lumbar region in a 67-year-old man. He complained of nocturia, frequent urination, and difficulty in walking for 2 months. Radiographic imaging revealed a lumbar spinal intradural mass. Intracranial lipid droplets dissemination was also existed. The patient underwent surgery, and a diagnosis of mature teratoma was confirmed histopathologically. During the operation, the cystic portion of the intradural mass ruptured. During the hospital stay, the patient's mental status declined. On radiological examination, slightly enlarged ventricle size was observed. Dissemination of lipid droplets within ventricles occurs because of spontaneous, iatrogenic, or traumatic rupture. Additional lipid droplet dissemination to the intracranial space associated with neurologic deterioration after a spinal teratoma surgery should be considered when iatrogenic rupture of the cyst portion occurs.
畸胎瘤是一种肿瘤,其在异位部位含有源自三个胚层的组织。畸胎瘤的胚胎学仍不清楚。畸胎瘤通常由囊性和实性成分组成,并且通常与脊髓空洞症相关。畸胎瘤的囊性病变可能以自发、医源性或创伤性方式破裂。脑室内和蛛网膜下腔中的脂质小滴很少见。我们诊治了一名67岁男性的腰椎脊髓畸胎瘤病例。他主诉夜尿、尿频和行走困难2个月。影像学检查显示腰椎椎管内硬膜下肿块。颅内也存在脂质小滴播散。患者接受了手术,组织病理学确诊为成熟畸胎瘤。手术过程中,硬膜下肿块的囊性部分破裂。住院期间,患者的精神状态下降。影像学检查发现脑室大小略有增大。脑室内脂质小滴播散是由于自发、医源性或创伤性破裂所致。当囊肿部分发生医源性破裂时,应考虑脊髓畸胎瘤手术后额外的脂质小滴播散至颅内空间并伴有神经功能恶化。