Department of Neurosurgery, Loma Linda University Medical Center, Loma Linda, CA, USA.
Spine (Phila Pa 1976). 2009 Dec 15;34(26):E973-8. doi: 10.1097/BRS.0b013e3181ba0fe5.
STUDY DESIGN.: Case report and literature review. OBJECTIVES.: To report the very rare case of a mature intramedullary teratoma with exophytic extension localized to the uppermost cervical spinal level in a 65-year-old woman and review the pertinent medical literature. SUMMARY OF BACKGROUND DATA.: Cervical intramedullary teratomas are extremely rare in adults, especially in patients older than 50 years. METHODS.: The patient presented with progressive ataxia, mild bilateral kinetic hand tremors, and dizziness. Magnetic resonance imaging revealed an intramedullary 1.7 x 1.3 x 2.3 cm mass at C1 with exophytic extension. A C1-C2 laminectomy and a partial suboccipital craniotomy were performed, followed by a subtotal microscopic resection of the tumor. Pathology was consistent with a mature teratoma. RESULTS.: After surgery, the patient's ataxia, tremor, and dizziness resolved almost immediately. CONCLUSION.: This report presents the very rare case of a mature intramedullary teratoma located in the upper cervical spine of an elderly patient, possibly the oldest patient documented with this type of lesion. The authors recommend a conservative subtotal surgical resection of cervical intramedullary tumors because it may improve symptoms that relate to direct mechanical cord compression and avoid further harm from a gross resection.
病例报告和文献复习。
报告一例非常罕见的 65 岁女性上颈段脊髓髓内外生性成熟畸胎瘤,并复习相关文献。
成人颈髓内畸胎瘤极为罕见,尤其是 50 岁以上的患者。
患者表现为进行性共济失调、双侧轻度动力性手震颤和头晕。磁共振成像显示 C1 水平脊髓内 1.7 x 1.3 x 2.3 cm 大小的肿块,有外生性延伸。行 C1-C2 椎板切除术和部分枕下颅骨切开术,然后对肿瘤进行部分显微镜下全切除。病理结果符合成熟畸胎瘤。
手术后,患者的共济失调、震颤和头晕几乎立即得到缓解。
本报告为一例非常罕见的老年患者上颈段脊髓髓内成熟畸胎瘤病例,可能是文献中记载的此类病变中最年长的患者。作者建议对颈髓内肿瘤进行保守性部分全切除术,因为它可以改善与直接机械性脊髓压迫相关的症状,并避免因大体全切除而造成进一步的损害。