Nickols Hilary Highfield, Chambless Lola B, Carson Robert P, Coffin Cheryl M, Pearson Matthew M, Abel Ty W
Department of Pathology, Division of Neuropathology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
J Neurosurg Pediatr. 2010 Dec;6(6):586-91. doi: 10.3171/2010.9.PEDS1022.
Intramedullary spinal cord teratomas are rare entities in infants. Management of these lesions is primarily surgical, with outcome dependent on rapid surgical decompression and complete gross-total tumor resection. The lesions are typically of the mature type, with immature teratomas displaying unique pathological features. The authors report a case of an extensive intramedullary immature teratoma in an infant with resolution of quadriplegia following gross-total radical resection. At the 1-year follow-up, there was radiographic evidence of tumor, and surgical reexploration yielded portions of immature teratoma and extensive gliosis.
脊髓髓内畸胎瘤在婴儿中是罕见的病变。这些病变的治疗主要是手术，其结果取决于快速的手术减压和肿瘤的完整全切。这些病变通常是成熟型的，未成熟畸胎瘤具有独特的病理特征。作者报告了一例婴儿广泛的髓内未成熟畸胎瘤病例，在肿瘤全切根治性切除后四肢瘫痪得到缓解。在1年的随访中，影像学显示有肿瘤迹象，再次手术探查发现了部分未成熟畸胎瘤和广泛的胶质增生。
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