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印度南部药学学士和药学博士学生对抗生素及耐药性的知识和态度,以及抗生素自我用药情况的比较。

Comparison of knowledge and attitudes about antibiotics and resistance, and antibiotics self-practicing between Bachelor of Pharmacy and Doctor of Pharmacy students in Southern India.

作者信息

Ahmad Akram, Khan Muhammad U, Moorthy Jagadeesan, Jamshed Shazia Q, Patel Isha

机构信息

Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, UCSI University . Kuala Lumpur ( Malaysia ).

Department of Pharmacy Practice, Bharat Institute of Technology-Pharmacy . Hyderabad ( India ).

出版信息

Pharm Pract (Granada). 2015 Jan-Mar;13(1):523. doi: 10.18549/pharmpract.2015.01.523. Epub 2015 Mar 15.

Abstract

BACKGROUND

There is limited research on pharmacy specialization based differences with regards to usage of antibiotics.

OBJECTIVE

To compare the knowledge, attitude and practice of Bachelor of Pharmacy (BPharm) and Doctor of Pharmacy (PharmD) students about usage and resistance of antibiotics in Southern India.

METHODS

This was a cross sectional study involving final year BPharm and PharmD students studying in two private institutions located in Andra Pradesh, India. The study was conducted for the period of 3 months. The questionnaire was divided into 5 components: demographics, knowledge about antibiotic use, attitude towards antibiotic use and resistance, self-antibiotic usage, and possible causes of antibiotic resistance. The study questionnaire was assessed for reliability. Data were analysed by employing Mann Whitney and chi square tests using SPSS version 19.

RESULTS

The sample size comprised of 137 students. The response rate was 76.11% for the study. There was a significant difference in the knowledge of antibiotic use in BPharm and PharmD students (Mean score: 5.09 vs 6.18, p<0.001). The overall attitude of PharmD students about antibiotic use and resistance was positive compared to BPharm students (Mean score: 3.05 vs 2.23, p<0.05). The self-antibiotic practices was higher in BPharm students than PharmD students (36.4% vs 20%, p<0.05). A significantly high number of PharmD students believed that empirical antibiotic therapy led to antibiotic resistance (19.5% versus 48%, P<0.05).

CONCLUSION

PharmD students were more knowledgeable about antibiotic usage and resistance compared to BPharm students who did not have accurate and the much needed information about the same. Future interventions should be targeted towards educating the BPharm students so that they can implement the acquired knowledge in their practice.

摘要

背景

关于抗生素使用方面药学专业差异的研究有限。

目的

比较印度南部药学学士(BPharm)和药学博士(PharmD)学生在抗生素使用及耐药性方面的知识、态度和实践。

方法

这是一项横断面研究,涉及在印度安得拉邦两所私立机构就读的最后一年BPharm和PharmD学生。研究为期3个月。问卷分为5个部分:人口统计学、抗生素使用知识、对抗生素使用和耐药性的态度、自我抗生素使用情况以及抗生素耐药性的可能原因。对研究问卷进行了信度评估。使用SPSS 19版通过曼-惠特尼检验和卡方检验分析数据。

结果

样本量包括137名学生。研究的回复率为76.11%。BPharm和PharmD学生在抗生素使用知识方面存在显著差异(平均得分:5.09对6.18,p<0.001)。与BPharm学生相比,PharmD学生对抗生素使用和耐药性的总体态度更为积极(平均得分:3.05对2.23,p<0.05)。BPharm学生的自我抗生素使用情况高于PharmD学生(36.4%对20%,p<0.05)。显著更多的PharmD学生认为经验性抗生素治疗会导致抗生素耐药性(19.5%对48%,P<0.05)。

结论

与没有准确且急需相关信息的BPharm学生相比,PharmD学生对抗生素使用和耐药性了解更多。未来的干预措施应针对教育BPharm学生,以便他们能够在实践中运用所学知识。

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