Ursem Carling J, Bosworth Hayden B, Shelby Rebecca A, Hwang Wenke, Anderson Roger T, Kimmick Gretchen G
1 Department of Hematology and Oncology, UCSF , San Francisco, California.
J Womens Health (Larchmt). 2015 May;24(5):403-8. doi: 10.1089/jwh.2014.4982. Epub 2015 Apr 17.
There are wide disparities in breast cancer-specific survival by patient sociodemographic characteristics. Women of lower income, for instance, have higher relapse and death rates from breast cancer. One possible contributing factor for this disparity is low use of adjuvant endocrine therapy-an extremely efficacious therapy in women with early stage, hormone receptor positive breast cancer, the most common subtype of breast cancer. Alone, adjuvant endocrine therapy decreases breast cancer recurrence by 50% and death by 30%. Data suggest that low use of adjuvant endocrine therapy is a potentially important and modifiable risk factor for poor outcome in low-income breast cancer patients.
乳腺癌患者的特定生存率因社会人口学特征存在巨大差异。例如,低收入女性乳腺癌复发和死亡率更高。造成这种差异的一个可能因素是辅助内分泌治疗的使用率低,而辅助内分泌治疗对早期激素受体阳性乳腺癌(乳腺癌最常见的亚型)女性极为有效。仅辅助内分泌治疗一项就能使乳腺癌复发率降低50%,死亡率降低30%。数据表明,辅助内分泌治疗使用率低是低收入乳腺癌患者预后不良的一个潜在重要且可改变的风险因素。