Amr Yasser Mohamed, Amin Sabry M
Department of Anesthesia, Tanta University Hospital, Tanta University, Tanta - 31527, Egypt.
Anesth Essays Res. 2010 Jan-Jun;4(1):25-8. doi: 10.4103/0259-1162.69302.
The I-gel mask is a novel supraglottic airway device. The objective of this study is to compare the insertion conditions for I-gel, using thiopental in two dosage regimes and propofol.
A prospective, randomized, double-blind design was used. Ninety patients included in the study were classified at induction into group I that received intravenous 2.5 mg.Kg-1 propofol, group II that received 6 mg.Kg-1 thiopental and group III that received 7 mg.Kg-1 thiopental. Mean arterial blood pressure (MABP) and heart rate (HR) were recorded immediately before, after insertion and 5 minutes later, as well as the baseline hemodynamic variables. Tolerance of I-gel insertion was assessed using a scoring system.
Insertion conditions for I-gel supraglottic airway device showed significantly higher incidence of jaw relaxation (P=0.0008, 0.02 in groups I and III, respectively). No significant difference was found in the incidence of breath holding, lacrimation and stridor between the groups (P>0.05). The incidence of coughing/movement was significantly less in groups I and III (P=0.012, 0.04, respectively). Insertion time was significantly less in groups I and III (P<0.0001). The changes in MABP and HR were significantly less in groups I and III (P<0.0001).
The use of thiopental at a dose of 7 mg.Kg-1 as an induction agent produced comparable I-gel supraglottic airway device insertion conditions with 2.5 mg.Kg-1 propofol in comparison to thiopental at 6 mg.Kg.-1.
I-gel面罩是一种新型的声门上气道装置。本研究的目的是比较在两种剂量方案下使用硫喷妥钠和丙泊酚时I-gel的插入情况。
采用前瞻性、随机、双盲设计。纳入研究的90例患者在诱导时被分为三组，第一组静脉注射2.5mg/kg丙泊酚，第二组静脉注射6mg/kg硫喷妥钠，第三组静脉注射7mg/kg硫喷妥钠。在插入前、插入后及5分钟后记录平均动脉血压（MABP）和心率（HR），以及基线血流动力学变量。使用评分系统评估I-gel插入的耐受性。
I-gel声门上气道装置的插入情况显示，下颌松弛的发生率显著更高（分别在第一组和第三组中P=0.0008、0.02）。各组间屏气、流泪和喘鸣的发生率无显著差异（P>0.05）。第一组和第三组咳嗽/运动的发生率显著更低（分别为P=0.012、0.04）。第一组和第三组的插入时间显著更短（P<0.0001）。第一组和第三组MABP和HR的变化显著更小（P<0.0001）。
与6mg/kg硫喷妥钠相比，使用7mg/kg硫喷妥钠作为诱导剂时，I-gel声门上气道装置的插入情况与2.5mg/kg丙泊酚相当。
