Patten Scott B, Williams Jeanne V A, Lavorato Dina H, Wang Jian Li, McDonald Keltie, Bulloch Andrew G M
Professor, Departments of Community Health Sciences and Psychiatry, University of Calgary, Calgary, Alberta; Member, Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta.
Research Associate, Department of Community Health Sciences, University of Calgary, Calgary, Alberta.
Can J Psychiatry. 2015 Jan;60(1):23-30. doi: 10.1177/070674371506000106.
The epidemiology of major depressive disorder (MDD) was first described in the Canadian national population in 2002. Updated information is now available from a 2012 survey: the Canadian Community Health Study-Mental Health (CCHS-MH).
The CCHS-MH employed an adaptation of the World Health Organization World Mental Health Composite International Diagnostic Interview and had a sample of n=25 113. Demographic variables, treatment, comorbidities, suicidal ideation, and perceived stigma were assessed. The analysis estimated adjusted and unadjusted frequencies and prevalence ratios. All estimates incorporated analysis methods to account for complex survey design effects.
The past-year prevalence of MDD was 3.9% (95% CI 3.5% to 4.2%). Prevalence was higher in women and in younger age groups. Among respondents with past-year MDD, 63.1% had sought treatment and 33.1% were taking an antidepressant (AD); 4.8% had past-year alcohol abuse and 4.5% had alcohol dependence. Among respondents with past-year MDD, the prevalence of cannabis abuse was 2.5% and that of dependence was 2.9%. For drugs other than cannabis, the prevalence of abuse was 2.3% and dependence was 2.9%. Generalized anxiety disorder was present in 24.9%. Suicide attempts were reported by 6.6% of respondents with past-year MDD. Among respondents accessing treatment, 37.5% perceived that others held negative opinions about them or treated them unfairly because of their disorder.
MDD is a common, burdensome, and stigmatized condition in Canada. Seeking help from professionals was reported at a higher frequency than in prior Canadian studies, but there has been no increase in AD use among Canadians with MDD.
2002年首次在加拿大全国人口中描述了重度抑郁症(MDD)的流行病学情况。现在有来自2012年一项调查的更新信息:加拿大社区健康调查-心理健康(CCHS-MH)。
CCHS-MH采用了世界卫生组织世界心理健康综合国际诊断访谈的改编版,样本量为n = 25113。评估了人口统计学变量、治疗情况、共病情况、自杀意念和感知到的污名。分析估计了调整和未调整的频率及患病率比。所有估计都纳入了分析方法以考虑复杂的调查设计效应。
过去一年MDD的患病率为3.9%(95%可信区间3.5%至4.2%)。患病率在女性和较年轻年龄组中更高。在过去一年患有MDD的受访者中,63.1%曾寻求治疗,33.1%正在服用抗抑郁药(AD);4.8%过去一年有酒精滥用,4.5%有酒精依赖。在过去一年患有MDD的受访者中,大麻滥用的患病率为2.5%,依赖率为2.9%。对于除大麻以外的其他药物,滥用患病率为2.3%,依赖率为2.9%。广泛性焦虑障碍的患病率为24.9%。过去一年患有MDD的受访者中有6.6%报告有自杀未遂。在接受治疗的受访者中,37.5%认为其他人因他们的疾病对他们持有负面看法或不公平对待他们。
在加拿大,MDD是一种常见、负担沉重且有污名化的疾病。报告寻求专业帮助的频率高于加拿大先前的研究,但患有MDD的加拿大人中抗抑郁药的使用没有增加。