一项关于公园遛狗作为接触耐药性肠外致病性大肠杆菌（ExPEC）风险因素的探索性研究。
An exploratory study of dog park visits as a risk factor for exposure to drug-resistant extra-intestinal pathogenic E. coli (ExPEC).
作者信息
Ahmed Lubna N, Price Lance B, Graham Jay P
机构信息
Department of Environmental & Occupational Health, Milken Institute School of Public Health, George Washington University, 950 New Hampshire Ave. NW, Washington, DC, 20052, USA.
出版信息
BMC Res Notes. 2015 Apr 10;8:137. doi: 10.1186/s13104-015-1103-2.
Abstract
BACKGROUND
Extraintestinal pathogenic E. coli (ExPEC) are common causative agents of urinary tract infections in humans. Dogs have been found to harbor ExPEC. This study tested stool samples from dogs (n = 16), the shoes of dog park visitors (n = 16) and the shoes of controls (n = 16) for ExPEC. Phenotypic resistance of isolates was characterized.
FINDINGS
ExPEC were present in one-third of the dog stool samples, 9% of the samples from the shoes of dog park visitors and 6% of control samples. Half of the ExPEC isolates were multi-drug resistant.
DISCUSSION
The findings suggest that dogs may be an important source of antibiotic resistant ExPEC.
摘要
背景
肠外致病性大肠杆菌（ExPEC）是人类尿路感染的常见病原体。已发现狗携带ExPEC。本研究检测了狗的粪便样本（n = 16）、狗狗公园访客的鞋子（n = 16）以及对照组的鞋子（n = 16）中的ExPEC。对分离株的表型耐药性进行了表征。
研究结果
三分之一的狗粪便样本、9%的狗狗公园访客鞋子样本和6%的对照样本中存在ExPEC。一半的ExPEC分离株具有多重耐药性。
讨论
研究结果表明，狗可能是抗生素耐药性ExPEC的重要来源。
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